Robert D Bjornson
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Explore the profile of Robert D Bjornson including associated specialties, affiliations and a list of published articles.
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16
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2610
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Recent Articles
1.
Burmeister A, Tzintzun-Tapia E, Roush C, Mangal I, Barahman R, Bjornson R, et al.
Appl Environ Microbiol
. 2023 May;
89(6):e0007923.
PMID: 37191555
Bacteriophages have received recent attention for their therapeutic potential to treat antibiotic-resistant bacterial infections. One particular idea in phage therapy is to use phages that not only directly kill their...
2.
Furey C, Choi J, Jin S, Zeng X, Timberlake A, Nelson-Williams C, et al.
Neuron
. 2018 Jul;
99(2):302-314.e4.
PMID: 29983323
Congenital hydrocephalus (CH), featuring markedly enlarged brain ventricles, is thought to arise from failed cerebrospinal fluid (CSF) homeostasis and is treated with lifelong surgical CSF shunting with substantial morbidity. CH...
3.
Jin S, Homsy J, Zaidi S, Lu Q, Morton S, DePalma S, et al.
Nat Genet
. 2017 Oct;
49(11):1593-1601.
PMID: 28991257
Congenital heart disease (CHD) is the leading cause of mortality from birth defects. Here, exome sequencing of a single cohort of 2,871 CHD probands, including 2,645 parent-offspring trios, implicated rare...
4.
Lee S, Seo J, Park J, Nam J, Choi A, Ignatius J, et al.
Sci Rep
. 2017 Jun;
7(1):4287.
PMID: 28655895
Despite efforts to interrogate human genome variation through large-scale databases, systematic preference toward populations of Caucasian descendants has resulted in unintended reduction of power in studying non-Caucasians. Here we report...
5.
Choi J, Goh G, Walradt T, Hong B, Bunick C, Chen K, et al.
Nat Genet
. 2015 Jul;
47(9):1011-9.
PMID: 26192916
Cutaneous T cell lymphoma (CTCL) is a non-Hodgkin lymphoma of skin-homing T lymphocytes. We performed exome and whole-genome DNA sequencing and RNA sequencing on purified CTCL and matched normal cells....
6.
Colangelo C, Shifman M, Cheung K, Stone K, Carriero N, Gulcicek E, et al.
Genomics Proteomics Bioinformatics
. 2015 Feb;
13(1):25-35.
PMID: 25712262
We report a significantly-enhanced bioinformatics suite and database for proteomics research called Yale Protein Expression Database (YPED) that is used by investigators at more than 300 institutions worldwide. YPED meets...
7.
Ryslik G, Cheng Y, Cheung K, Bjornson R, Zelterman D, Modis Y, et al.
BMC Bioinformatics
. 2014 Jul;
15:231.
PMID: 24990767
Background: Current research suggests that a small set of "driver" mutations are responsible for tumorigenesis while a larger body of "passenger" mutations occur in the tumor but do not progress...
8.
Ni T, Landrette S, Bjornson R, Bosenberg M, Xu T
Proc Natl Acad Sci U S A
. 2013 Sep;
110(38):E3640-9.
PMID: 24003131
Despite considerable efforts to sequence hypermutated cancers such as melanoma, distinguishing cancer-driving genes from thousands of recurrently mutated genes remains a significant challenge. To circumvent the problematic background mutation rates...
9.
Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton J, et al.
Nature
. 2013 May;
498(7453):220-3.
PMID: 23665959
Congenital heart disease (CHD) is the most frequent birth defect, affecting 0.8% of live births. Many cases occur sporadically and impair reproductive fitness, suggesting a role for de novo mutations....
10.
Sanders S, Murtha M, Gupta A, Murdoch J, Raubeson M, Willsey A, et al.
Nature
. 2012 Apr;
485(7397):237-41.
PMID: 22495306
Multiple studies have confirmed the contribution of rare de novo copy number variations to the risk for autism spectrum disorders. But whereas de novo single nucleotide variants have been identified...