Robert C Sharp
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Explore the profile of Robert C Sharp including associated specialties, affiliations and a list of published articles.
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10
Citations
143
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Recent Articles
1.
Sharp R, Guenther D, Farrer M
Front Immunol
. 2023 Nov;
14:1281705.
PMID: 38022545
Objective: The aim of this study was to systematically review the neuroimmunology literature to determine the average immune cell counts reported by flow cytometry in wild-type (WT) homogenized mouse brains....
2.
Khosravi-Maharlooei M, Madley R, Borsotti C, Ferreira L, Sharp R, Brehm M, et al.
Mol Metab
. 2021 Dec;
56:101417.
PMID: 34902607
Background: Type 1 diabetes (T1D) is an autoimmune disease characterized by impaired immune tolerance to β-cell antigens and progressive destruction of insulin-producing β-cells. Animal models have provided valuable insights for...
3.
Sharp R, Brown M, Shapiro M, Posgai A, Brusko T
Front Immunol
. 2021 Oct;
12():739048.
PMID: 34603322
Background: The pathogenesis of type 1 diabetes (T1D) involves complex genetic susceptibility that impacts pathways regulating host immunity and the target of autoimmune attack, insulin-producing pancreatic β-cells. Interactions between risk...
4.
Shapiro M, Thirawatananond P, Peters L, Sharp R, Ogundare S, Posgai A, et al.
Immunol Cell Biol
. 2021 Jan;
99(5):496-508.
PMID: 33483996
The conceptual basis for a genetic predisposition underlying the risk for developing type 1 diabetes (T1D) predates modern human molecular genetics. Over half of the genetic risk has been attributed...
5.
Naser A, Odeh A, Sharp R, Qasem A, Beg S, Naser S
Microorganisms
. 2019 Dec;
7(12).
PMID: 31817071
We previously discovered that single nucleotide polymorphisms (SNPs) in (T-cell negative-regulators) occur in 78% of rheumatoid arthritis (RA), along with (MAP) infection in 33% of patients. In Crohn's disease, we...
6.
Sharp R, Naser E, Alcedo K, Qasem A, Abdelli L, Naser S
Gut Pathog
. 2018 Dec;
10:51.
PMID: 30534203
Background: Several pathogens have been debated to play a role in inflammatory bowel disease (IBD) including Crohn's disease (CD). None of these pathogens have been investigated together in same clinical...
7.
Cao B, Qasem A, Sharp R, Abdelli L, Naser S
World J Gastroenterol
. 2018 Jul;
24(25):2764-2775.
PMID: 29991880
Aim: To perform a meta-analysis on the risk of developing (TB) infection in Crohn's disease (CD) patients treated with tumor necrosis factor-alpha (TNFα) inhibitors. Methods: A meta-analysis of randomized, double-blind,...
8.
Sharp R, Beg S, Naser S
World J Gastroenterol
. 2018 Feb;
24(6):657-670.
PMID: 29456405
Aim: To establish the relationship of () polymorphisms and mycobacterial infections in Crohn's disease (CD). Methods: All 133 subjects' blood samples were genotyped for nine single nucleotide polymorphisms (SNPs) in...
9.
Sharp R, Beg S, Naser S
Front Cell Infect Microbiol
. 2018 Feb;
8:11.
PMID: 29423382
A shared genetic pre-disposition, chronic inflammation, and treatment with similar biologics between Rheumatoid arthritis (RA) and Crohn's disease (CD) have intrigued us to investigate whether the two disorders share trigger...
10.
Sharp R, Abdulrahim M, Naser E, Naser S
Front Cell Infect Microbiol
. 2016 Jan;
5:95.
PMID: 26734582
Genome wide association studies have identified several genes that might be associated with increase susceptibility to Type 1 Diabetes (T1D) and Crohn's disease. Both Crohn's disease and T1D have a...