Robert Barrett
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Explore the profile of Robert Barrett including associated specialties, affiliations and a list of published articles.
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23
Citations
1070
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Recent Articles
1.
Chesnokova V, Zonis S, Apaydin T, Barrett R, Melmed S
Aging Cell
. 2024 May;
23(8):e14193.
PMID: 38724466
DNA damage-induced senescence is initially sustained by p53. Senescent cells produce a senescence-associated secretory phenotype (SASP) that impacts the aging microenvironment, often promoting cell transformation. Employing normal non-tumorous human colon...
2.
Kirkpatrick A, McKee J, Barrett R, Couperus K, Wachs J
Can J Surg
. 2023 Nov;
66(6):E522-E534.
PMID: 37914210
People suffering from critical injuries/illness face marked challenges before transportation to definitive care. Solutions to diagnose and intervene in the prehospital setting are required to improve outcomes. Despite advances in...
3.
Apaydin T, Zonis S, Zhou C, Valencia C, Barrett R, Strous G, et al.
iScience
. 2023 Oct;
26(11):108117.
PMID: 37876819
DNA damage repair (DDR) is mediated by phosphorylating effectors ATM kinase, CHK2, p53, and γH2AX. We showed earlier that GH suppresses DDR by suppressing pATM, resulting in DNA damage accumulation....
4.
Vitamin D Status and Mortality from SARS CoV-2: A Prospective Study of Unvaccinated Caucasian Adults
Barrett R, Youssef M, Shah I, Ioana J, Al Lawati A, Bukhari A, et al.
Nutrients
. 2022 Aug;
14(16).
PMID: 36014757
COVID-19 and a low vitamin D state share common risk factors, which might explain why vitamin D deficiency has been linked with higher COVID-19 mortality. Moreover, measures of serum vitamin...
5.
Chesnokova V, Zonis S, Apostolou A, Estrada H, Knott S, Wawrowsky K, et al.
Cell Rep
. 2021 Dec;
37(11):110068.
PMID: 34910915
Microenvironmental factors modulating age-related DNA damage are unclear. Non-pituitary growth hormone (npGH) is induced in human colon, non-transformed human colon cells, and fibroblasts, and in 3-dimensional intestinal organoids with age-associated...
6.
Barrett R, Barrett R
Expert Rev Respir Med
. 2021 Sep;
15(12):1605-1612.
PMID: 34555287
Background: During the pandemic, there have been disruptions to how patients seek care. Research Design And Methods: To investigate monthly prescription claims for asthma and chronic obstructive pulmonary disease (COPD)...
7.
Barrett R, Barrett R, Dhar K, Birch B
BJUI Compass
. 2021 Sep;
2(6):419-427.
PMID: 34518826
Objective: To examine the effect of the COVID-19 pandemic on gonadorelin analogue prescription for community patients in England. Materials And Methods: We included data from all primary-care patients who had...
8.
Chesnokova V, Zonis S, Barrett R, Kameda H, Wawrowsky K, Ben-Shlomo A, et al.
JCI Insight
. 2019 Feb;
4(3).
PMID: 30728323
Growth hormone (GH) decreases with age, and GH therapy has been advocated by some to sustain lean muscle mass and vigor in aging patients and advocated by athletes to enhance...
9.
Akhtar A, Sances S, Barrett R, Breunig J
Curr Stem Cell Rep
. 2017 Oct;
3(2):98-111.
PMID: 28983454
Purpose Of Review: The modeling of biological processes provides an important tool to better understand mechanisms of development and disease, allowing for the rapid testing of therapeutics. However, a critical...
10.
Yucer N, Holzapfel M, Vogel T, Lenaeus L, Ornelas L, Laury A, et al.
Sci Rep
. 2017 Sep;
7(1):10741.
PMID: 28878359
The fallopian tube epithelium (FTE) has been recognized as a site of origin of high-grade serous ovarian cancer (HGSC). However, the absence of relevant in vitro human models that can...