Robert B Levy
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Explore the profile of Robert B Levy including associated specialties, affiliations and a list of published articles.
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64
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1379
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Recent Articles
1.
McManus D, Copsel S, Pffeifer B, Wolf D, Barreras H, Ma S, et al.
bioRxiv
. 2025 Feb;
PMID: 39896683
The current approach to minimize transplant-associated complications, including graft-versus-host disease (GVHD) includes long-term pharmacological immune suppression frequently accompanied by unwanted side effects. Advances in targeted immunotherapies regulating alloantigen responses in...
2.
Copsel S, Garrido V, Barreras H, Bader C, Pfeiffer B, Mateo-Victoriano B, et al.
JCI Insight
. 2024 Apr;
9(9).
PMID: 38602775
Allogeneic hematopoietic stem cell transplantation (aHSCT) can cure patients with otherwise fatal leukemias and lymphomas. However, the benefits of aHSCT are limited by graft-versus-host disease (GVHD). Minnelide, a water-soluble analog...
3.
Barreras H, Copsel S, Bader C, Ding Y, Wolf D, Cash C, et al.
Transplant Cell Ther
. 2023 Feb;
29(5):341.e1-341.e9.
PMID: 36804930
The present studies examined experimental transplant outcomes using mobilized peripheral blood from mice and humans together with FoxP3+Treg cells. Donor mice were treated with filgrastim and / or plerixafor and...
4.
Neophytou D, Arribas D, Arora T, Levy R, Park I, Oviedo H
PLoS Biol
. 2022 Oct;
20(10):e3001803.
PMID: 36269764
Brain asymmetry in the sensitivity to spectrotemporal modulation is an established functional feature that underlies the perception of speech and music. The left auditory cortex (ACx) is believed to specialize...
5.
Perez V, Mousa H, Soifer M, Beatty C, Sarantopoulos S, Saban D, et al.
Am J Ophthalmol
. 2022 Sep;
247:42-60.
PMID: 36162534
Purpose: To investigate the role of aggressive meibomian gland dysfunction (MGD) in the immune pathogenesis of ocular graft-vs-host disease (GVHD). Methods: In mice, an allogeneic GVHD model was established by...
6.
Copsel S, Wolf D, Pfeiffer B, Barreras H, Perez V, Levy R
Front Immunol
. 2022 Jul;
13:932527.
PMID: 35799783
Human and mouse CD4FoxP3 T cells (Tregs) comprise non-redundant regulatory compartments which maintain self-tolerance and have been found to be of potential therapeutic usefulness in autoimmune disorders and transplants including...
7.
Wolf D, Barreras H, Copsel S, Komanduri K, Levy R
Transplant Cell Ther
. 2022 Mar;
28(6):303.e1-303.e7.
PMID: 35302008
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is complicated by graft- versus-host disease (GVHD), which causes immune dysfunction and further delays immune reconstitution through its effects on primary and secondary lymphoid...
8.
Lam B, Feuer W, Davis J, Porciatti V, Yu H, Levy R, et al.
Am J Ophthalmol
. 2022 Mar;
241:262-271.
PMID: 35271811
Purpose: To assess safety of gene therapy in G11778A Leber hereditary optic neuropathy (LHON). Design: Phase 1 clinical trial. Methods: Setting: single institution. Participants: Patients with G11778A LHON and chronic...
9.
Levy R, Mousa H, Lightbourn C, Shiuey E, Latoni D, Duffort S, et al.
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008621
Graft versus host disease (GVHD) is initiated by donor allo-reactive T cells activated against recipient antigens. Chronic GVHD (cGVHD) is characterized by immune responses that may resemble autoimmune features present...
10.
Soifer M, Mousa H, Levy R, Perez V
Front Med (Lausanne)
. 2021 Jun;
8:656998.
PMID: 34095169
Stevens Johnsons syndrome (SJS) is a mucocutaneous disorder caused by an autoimmune response most commonly to medications. Unless it is properly managed in the acute setting, this entity can affect...