Robert A Mitchell
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Explore the profile of Robert A Mitchell including associated specialties, affiliations and a list of published articles.
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72
Citations
3308
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Recent Articles
1.
Mitchell R, Macia D, Jairoce C, Mpina M, Naidu A, Chopo-Pizarro A, et al.
NPJ Vaccines
. 2024 Oct;
9(1):200.
PMID: 39455625
RTS,S/AS01, the first approved malaria vaccine, demonstrated moderate efficacy during the phase 3 pediatric trial. We previously investigated cell-mediated immune (CMI) responses following the primary 3-dose immunization and now report...
2.
Spertini C, Benechet A, Birch F, Bellotti A, Roman-Trufero M, Arber C, et al.
Cell Death Discov
. 2024 Mar;
10(1):157.
PMID: 38548753
The malignant microenvironment plays a major role in the development of resistance to therapies and the occurrence of relapses in acute myeloid leukemia (AML). We previously showed that interactions of...
3.
Mitchell R, Ubillos I, Requena P, Campo J, Ome-Kaius M, Hanieh S, et al.
Clin Exp Immunol
. 2024 Feb;
216(2):172-191.
PMID: 38387476
Chronic immune activation from persistent malaria infections can induce immunophenotypic changes associated with T-cell exhaustion. However, associations between T and B cells during chronic exposure remain undefined. We analyzed peripheral...
4.
Sarkar O, Donninger H, Al Rayyan N, Chew L, Stamp B, Zhang X, et al.
Sci Adv
. 2023 Jun;
9(26):eadg3736.
PMID: 37390211
Immune checkpoint inhibitor (ICI) therapy is effective against many cancers for a subset of patients; a large percentage of patients remain unresponsive to this therapy. One contributing factor to ICI...
5.
Woeste M, Shrestha R, Geller A, Li S, Montoya-Durango D, Ding C, et al.
J Immunother Cancer
. 2023 Apr;
11(4).
PMID: 37072351
Background: Pancreatic cancer (PC) is a challenging diagnosis that is yet to benefit from the advancements in immuno-oncologic treatments. Irreversible electroporation (IRE), a non-thermal method of tumor ablation, is used...
6.
Noe J, Ding C, Geller A, Rendon B, Yan J, Mitchell R
Bio Protoc
. 2023 Mar;
13(5).
PMID: 36908637
A rigorous determination of effector contributions of tumor-infiltrating immune cells is critical for identifying targetable molecular mechanisms for the development of novel cancer immunotherapies. A tumor/immune cell-admixture model is an...
7.
Thiele M, Donnelly S, Mitchell R
J Immunother Cancer
. 2022 Sep;
10(9).
PMID: 36180072
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with a pleiotropic spectrum of biological functions implicated in the pathogenesis of cancer and inflammatory diseases. MIF is constitutively present in...
8.
Dobano C, Ramirez-Morros A, Alonso S, Ruiz-Olalla G, Rubio R, Vidal M, et al.
Immunology
. 2022 Sep;
167(4):528-543.
PMID: 36065677
We evaluated the kinetics of antibody responses to Two years into the COVID-19 pandemic and 1 year after the start of vaccination rollout, the world faced a peak of cases...
9.
Mitchell R, Altszuler R, Gonzalez S, Johnson R, Frevert U, Nardin E
Front Immunol
. 2022 Jun;
13:801111.
PMID: 35734173
The skin is the site of host invasion by the mosquito-borne parasite, which caused an estimated 229 million infections and 409,000 deaths in 2019 according to WHO World Malaria report...
10.
Geller A, Shrestha R, Woeste M, Guo H, Hu X, Ding C, et al.
Nat Commun
. 2022 Feb;
13(1):759.
PMID: 35140221
Despite the remarkable success of immunotherapy in many types of cancer, pancreatic ductal adenocarcinoma has yet to benefit. Innate immune cells are critical to anti-tumor immunosurveillance and recent studies have...