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Rob Tibshirani

Explore the profile of Rob Tibshirani including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 8788
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Recent Articles
1.
Strand S, Rivero-Gutierrez B, Houlahan K, Seoane J, King L, Risom T, et al.
Cancer Cell . 2023 Jul; 41(7):1381. PMID: 37433282
No abstract available.
2.
Strand S, Rivero-Gutierrez B, Houlahan K, Seoane J, King L, Risom T, et al.
Cancer Cell . 2022 Nov; 40(12):1521-1536.e7. PMID: 36400020
Ductal carcinoma in situ (DCIS) is the most common precursor of invasive breast cancer (IBC), with variable propensity for progression. We perform multiscale, integrated molecular profiling of DCIS with clinical...
3.
Cramer E, Ray E, Lopez V, Bracher J, Brennen A, Castro Rivadeneira A, et al.
Proc Natl Acad Sci U S A . 2022 Apr; 119(15):e2113561119. PMID: 35394862
Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both...
4.
Aguirre M, Tanigawa Y, Venkataraman G, Tibshirani R, Hastie T, Rivas M
Eur J Hum Genet . 2021 Feb; 29(7):1071-1081. PMID: 33558700
Polygenic risk models have led to significant advances in understanding complex diseases and their clinical presentation. While polygenic risk scores (PRS) can effectively predict outcomes, they do not generally account...
5.
Biggerstaff M, Johansson M, Alper D, Brooks L, Chakraborty P, Farrow D, et al.
Epidemics . 2018 Mar; 24:26-33. PMID: 29506911
Accurate forecasts could enable more informed public health decisions. Since 2013, CDC has worked with external researchers to improve influenza forecasts by coordinating seasonal challenges for the United States and...
6.
Aghaeepour N, Lehallier B, Baca Q, Ganio E, Wong R, Ghaemi M, et al.
Am J Obstet Gynecol . 2017 Dec; 218(3):347.e1-347.e14. PMID: 29277631
Background: Early detection of maladaptive processes underlying pregnancy-related pathologies is desirable because it will enable targeted interventions ahead of clinical manifestations. The quantitative analysis of plasma proteins features prominently among...
7.
Simon N, Friedman J, Hastie T, Tibshirani R
J Stat Softw . 2016 Apr; 39(5):1-13. PMID: 27065756
We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of ℓ and ℓ penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and...
8.
Reid S, Tibshirani R
J Stat Softw . 2015 Aug; 58(12). PMID: 26257587
We apply the cyclic coordinate descent algorithm of Friedman, Hastie, and Tibshirani (2010) to the fitting of a conditional logistic regression model with lasso [Formula: see text] and elastic net...
9.
Ganjoo K, Witten D, Patel M, Espinosa I, La T, Tibshirani R, et al.
Am J Clin Oncol . 2013 Jun; 34(1):82-6. PMID: 23781555
Introduction: High numbers of tumor-associated macrophages (TAMs) have been associated with poor outcome in several solid tumors. In 2 previous studies, we showed that colony stimulating factor-1 (CSF1) is secreted...
10.
Alencar A, Malumbres R, Kozloski G, Advani R, Talreja N, Chinichian S, et al.
Clin Cancer Res . 2011 Apr; 17(12):4125-35. PMID: 21525173
Purpose: Diffuse large B-cell lymphoma (DLBCL) heterogeneity has prompted investigations for new biomarkers that can accurately predict survival. A previously reported 6-gene model combined with the International Prognostic Index (IPI)...