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Rituraj Purohit

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Articles 115
Citations 2064
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Recent Articles
1.
Singh R, Purohit R
Biochem Biophys Res Commun . 2025 Mar; 756:151575. PMID: 40064092
Mycobacterium tuberculosis (MTB), the pathogen responsible for tuberculosis (TB), remains a significant global health concern, especially with the growing prevalence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains. This study...
2.
Singh S, Sendri N, Sharma B, Kumar P, Sharma A, Tirpude N, et al.
Food Res Int . 2025 Jan; 200():115427. PMID: 39779086
Anthocyanins (ANS) are an appealing substitute to synthetic colorants; but their practical applicability is limited due to low color stability. Copigmentation can improve both complex's color stability as well as...
3.
Daroch A, Purohit R
Int J Biol Macromol . 2024 Dec; 287():138580. PMID: 39657879
MicroRNAs (miRNAs) are important in gene expression regulation and many other biological processes and have emerged as promising therapeutic targets. Identifying potential drug-miRNA relationships is helpful in disease therapy and...
4.
Yamini , Anand P, Bhardwaj V, Kumar A, Purohit R, Das P, et al.
J Biomol Struct Dyn . 2024 Nov; 42(21):11954-11975. PMID: 39540409
Head and neck Squamous Cell Carcinoma (HNSCC) is a growing concern worldwide and MAPKAPK2/MK2 (Mitogen-Activated Protein Kinase Activated Protein Kinase 2) is crucially involved in HNSCC progression. Increased disease burden...
5.
Kumar P, Bhardwaj V, Shende P, Purohit R
Eur J Pharm Biopharm . 2024 Oct; 205:114569. PMID: 39481614
Investigating the structural stability of poorly-soluble luteolin (LuT) after encapsulation within cyclodextrins (CDs) is crucial for unlocking the therapeutic potential of LuT bioactive molecule. Herein, native and modified β-CD were...
6.
Kumar P, Purohit R
Carbohydr Polym . 2024 Jul; 342:122350. PMID: 39048216
Piperine (PiP), a bioactive molecule, exhibits numerous health benefits and is frequently employed as a co-delivery agent with various phytomedicines (e.g., curcumin) to enhance their bioavailability. This is attributed to...
7.
Gupta A, Purohit R
J Cell Biochem . 2024 Feb; 125(3):e30532. PMID: 38317535
In the present work a combination of traditional and steered molecular dynamics based techniques were employed to identify potential inhibitors against the human BRD4 protein (BRD4- BD1); an established drug...
8.
Singh R, Manna S, Nandanwar H, Purohit R
Microbes Infect . 2023 Dec; 26(3):105279. PMID: 38128751
Tuberculosis is a contagious bacterial ailment that primarily affects the lungs and is brought on by the bacterium Mycobacterium tuberculosis (MTB). An antimycobacterial medication called bedaquiline (BQ) is specified to...
9.
Kazi J, Al Ashiri L, Purohit R, Ronnstrand L
Cancers (Basel) . 2023 Nov; 15(22). PMID: 38001685
The type III receptor tyrosine kinase FLT3 is a pivotal kinase for hematopoietic progenitor cell regulation, with significant implications in acute myeloid leukemia (AML) through mutations like internal tandem duplication...
10.
Kumar P, Bhardwaj V, Purohit R
Carbohydr Polym . 2023 Nov; 323:121432. PMID: 37940299
The poor aqueous solubility of curcumin (CUR) obstructs its wide utilization in nutraceuticals, cosmetics, and pharmaceutical companies. This study is dedicated to investigate the stability of CUR inside the hydrophobic...