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Ritu Prajapati

Explore the profile of Ritu Prajapati including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 31
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Recent Articles
1.
Weirath N, Zajac J, Donow H, Lavoi T, Pinilla C, Santos R, et al.
J Med Chem . 2025 Jan; 68(3):2504-2527. PMID: 39832483
The melanocortin receptors are a class of centrally and peripherally expressed G protein-coupled receptors, of which the MC3R and MC4R subtypes are implicated in the regulation of appetite and energy...
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Nam Y, Prajapati R, Kim S, Shin S, Cheong D, Park Y, et al.
Biomed Pharmacother . 2024 Feb; 172:116226. PMID: 38301421
Alzheimer's disease (AD) is characterized by the presence of two critical pathogenic factors: amyloid-β (Aβ) and tau. Aβ and tau become neurotoxic aggregates via self-assembly, and these aggregates contribute to...
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Paudel P, Choi J, Prajapati R, Seong S, Park S, Kang W, et al.
Int J Mol Sci . 2023 Nov; 24(21). PMID: 37958841
Natural flavone and isoflavone analogs such as 3',4',7-trihydroxyflavone (), 3',4',7-trihydroxyisoflavone (), and calycosin () possess significant neuroprotective activity in Alzheimer's and Parkinson's disease. This study highlights the in vitro human...
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Lim H, Prajapati R, Seong S, Jung H, Choi J
ACS Omega . 2023 Feb; 8(7):6538-6549. PMID: 36844518
Aglycone- and glycoside-derived forms of flavonoids exist broadly in plants and foods such as fruits, vegetables, and peanuts. However, most studies focus on the bioavailability of flavonoid aglycone rather than...
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Kim S, Nam Y, Shin S, Prajapati R, Shin S, Kim M, et al.
Biomed Pharmacother . 2022 Oct; 156:113865. PMID: 36242849
A prominent characteristic of Alzheimer's disease (AD) is the deposition of both amyloid-β (Aβ) peptide and tau protein in the brain. Aβ and tau not only induce toxicity through self-aggregation...
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Ha M, Lee T, Kim C, Prajapati R, Kim J, Choi J, et al.
Phytochemistry . 2022 Feb; 197:113100. PMID: 35144153
In this study, we present the first investigation of Hedera rhombea Bean fruit, which led to the isolation of six undescribed compounds including two megastigmane glucosides, two rare 1,4-dioxane neolignanes,...
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Prajapati R, Seong S, Paudel P, Park S, Jung H, Choi J
ACS Omega . 2021 Dec; 6(49):33443-33453. PMID: 34926894
Alterations in the expression and/or activity of brain G-protein-coupled receptors (GPCRs) such as dopamine DR, DR, DR, and DR, vasopressin VR, and serotonin 5-HTR are noted in various neurodegenerative diseases...
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Prajapati R, Seong S, Park S, Paudel P, Jung H, Choi J
Sci Rep . 2021 Dec; 11(1):23528. PMID: 34876600
Isoliquiritigenin (= 4,2',4'-Trihydroxychalcone) (ILG) is a major constituent of the Glycyrrhizae Rhizoma that has significant neuroprotective functions. In the present study, we re-examined the potential of ILG to inhibit human...
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Prajapati R, Park S, Seong S, Paudel P, Mohd Fauzi F, Jung H, et al.
Biomolecules . 2021 Aug; 11(7). PMID: 34356625
Monoamine oxidases (MAOs) and muscarinic acetylcholine receptors (mAChRs) are considered important therapeutic targets for Parkinson's disease (PD). Lipophilic tanshinones are major phytoconstituents in the dried roots of that have demonstrated...