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Rita M Borik

Explore the profile of Rita M Borik including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 45
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Recent Articles
1.
Borik R, Hussein M
Curr Pharm Des . 2024 Nov; PMID: 39506445
Background: PGK1 and PKM2 are glycolytic enzymes, and their expression is upregulated in cancer cells. STAT3 is a transcription factor implicated in breast cancer progression and chemoresistance. Researchers worldwide continue...
2.
El-Wahab A, Borik R, Al-Dies A, Fouda A, Mohamed H, El-Eisawy R, et al.
Sci Rep . 2024 Apr; 14(1):9862. PMID: 38684707
The process of creating a series of 3-amino-1-aryl-8-methoxy-1H-benzo[f]chromene-2-carbonitriles (4a-q) involved reacting 6-methoxynaphthalen-2-ol (1), the appropriate aromatic aldehydes (2a-q), and malononitrile (3) in an absolute ethanol/piperidine solution under Ultrasonic irradiation. However,...
3.
Hussein M, Borik R, Nafie M, Abo-Salem H, Boshra S, Mohamed Z
Molecules . 2023 Aug; 28(16). PMID: 37630304
The current work was conducted to synthesize several novel anti-inflammatory quinazolines having sulfamerazine moieties as new 3CLpro, cPLA2, and sPLA2 inhibitors. The thioureido derivative was formed when compound was treated...
4.
Hussein M, Ismail N, Mohamed A, Borik R, Ali A, Mosaad Y
Bioinform Biol Insights . 2021 Nov; 15:11779322211055891. PMID: 34840499
Background: Coronavirus-19 (COVID-19) pandemic is a worldwide public health problem that has been known in China since December 25, 2019. Phospholipids are structural components of the mammalian cytoskeleton and cell...
5.
Borik R, Hussein M
Curr Pharm Biotechnol . 2021 Jun; 23(9):1179-1203. PMID: 34077343
Background: Quinazolines are a common class of nitrogen-containing heterocyclic scaffolds, which exhibit a broad spectrum of pharmacological activities. Objectives: In the present study, quinazoline and quinazolin-4-one derivatives were prepared, characterized,...
6.
Borik R, Fawzy N, Abu-Bakr S, Aly M
Molecules . 2018 Jun; 23(6). PMID: 29890691
Curcumin, a widely utilized flavor and coloring agent in food, has been shown to demonstrate powerful antioxidant, antitumor promoting and anti-inflammatory properties in vitro and in vivo. In the present...
7.
M Al-Zaydi K, Borik R, Mekheimer R, Elnagdi M
Ultrason Sonochem . 2010 Jan; 17(5):909-15. PMID: 20064736
A facile, solvent free, ecofriendly approach for the synthesis of pyridine-2,6-diones 4a-d, pyridazinone derivatives 8a-c and thienoazines 6 and 9 is herein described employing neat reaction conditions under both microwave...
8.
M Al-Zaydi K, Borik R, Elnagdi M
Ultrason Sonochem . 2008 Dec; 16(5):660-8. PMID: 19112037
A variety of arylhydrazonopyridinones were prepared via heating cyanoacetamides with ethyl acetoacetate in absence of solvent under reflux conventionally or ultrasound irradiation or in a microwave oven. The formed products...
9.
M Al-Zaydi K, Borik R
Molecules . 2007 Oct; 12(8):2061-79. PMID: 17960106
The reaction of methyl ketones 1a-g with dimethylformamide dimethylacetal (DMFDMA) afforded the enaminones 2a-g, which were coupled with diazotized aromatic amines 3a,b to give the corresponding aryl hydrazones 6a-h. Condensation...