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Risna Kanjirassery Radhakrishnan

Explore the profile of Risna Kanjirassery Radhakrishnan including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 93
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Recent Articles
1.
Radhakrishnan R, Ravichandran S, Sukesh A, Kadalmani B, Kandasamy M
Lab Anim Res . 2022 Mar; 38(1):7. PMID: 35246277
Background: Botulinum toxin (BoNT) is a widely used therapeutic agent that blocks the excessive release of acetylcholine at the neuromuscular junction. Previously, repeated intracremasteric injections and slight overdose of BoNT...
2.
Yesudhas A, Radhakrishnan R, Sukesh A, Ravichandran S, Manickam N, Kandasamy M
Biochem Biophys Res Commun . 2021 Jul; 569:54-60. PMID: 34229123
Cholinergic crisis and oxidative stress in the hippocampus of the brain have been known to induce anxiety disorders upon ageing. BOTOX® is a widely used therapeutic form of botulinum neurotoxin...
3.
Sri Rethinavel H, Ravichandran S, Radhakrishnan R, Kandasamy M
J Chem Neuroanat . 2021 May; 115:101965. PMID: 33989761
Anosmia, a neuropathogenic condition of loss of smell, has been recognized as a key pathogenic hallmark of the current pandemic SARS-CoV-2 infection responsible for COVID-19. While the anosmia resulting from...
4.
Selvaraj K, Ravichandran S, Krishnan S, Radhakrishnan R, Manickam N, Kandasamy M
Reprod Sci . 2021 Jan; 28(10):2735-2742. PMID: 33415647
Coronavirus disease 2019 (COVID-19), which resulted from the pandemic outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes a massive inflammatory cytokine storm leading to multi-organ damage including...
5.
Manickam N, Radhakrishnan R, Vergil Andrews J, Selvaraj D, Kandasamy M
Life Sci . 2020 Oct; 263:118569. PMID: 33049278
Huntington's disease (HD) is an autosomal dominant pathogenic condition that causes progressive degeneration of GABAergic neurons in the brain. The abnormal expansion of the CAG repeats in the exon 1...
6.
Yesudhas A, Roshan S, Radhakrishnan R, Abirami G, Manickam N, Selvaraj K, et al.
Neurochem Res . 2020 Sep; 45(12):2856-2867. PMID: 32974763
BOTOX® is a therapeutic form of botulinum neurotoxin. It acts by blocking the release of acetylcholine (ACh) from the synaptic vesicles at the neuromuscular junctions, thereby inhibiting the muscle contraction....
7.
Abirami G, Radhakrishnan R, Johnson E, Roshan S, Yesudhas A, Parveen S, et al.
Adv Neurobiol . 2020 Feb; 24:207-222. PMID: 32006362
Autism spectrum disorder (ASD) encompasses a cluster of neurodevelopmental and genetic disorders that has been characterized mainly by social withdrawal, repetitive behavior, restricted interests, and deficits in language processing mainly ...
8.
Selvaraj K, Manickam N, Kumaran E, Thangadurai K, Elumalai G, Sekar A, et al.
J Steroid Biochem Mol Biol . 2019 Nov; 197:105526. PMID: 31715317
Huntington's disease (HD) is an autosomal dominant progressive neurodegenerative disorder mainly affecting the structure and functions of the striatum, cerebral cortex and hippocampus leading to movement disorders, cognitive dysfunctions and...
9.
Kandasamy M, Radhakrishnan R, Abirami G, Roshan S, Yesudhas A, Balamuthu K, et al.
Neurochem Res . 2019 Jun; 44(8):1781-1795. PMID: 31254250
The hippocampus-derived neuroestradiol plays a major role in neuroplasticity, independent of circulating estradiol that originates from gonads. The response of hypothalamus-pituitary regions towards the synthesis of neuroestradiol in the hippocampus...
10.
Kandasamy M, Yesudhas A, Abirami G, Radhakrishnan R, Roshan S, Johnson E, et al.
Med Hypotheses . 2019 May; 127:105-111. PMID: 31088631
Neural stem cell (NSC) mediated adult neurogenesis represents the regenerative plasticity of the brain. The functionality of the neurogenic process appears to be operated by neuroblasts, the multipotent immature neuronal...