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Rishi Patel

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Articles 97
Citations 772
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Recent Articles
1.
Baffour K, Koti N, Nyabayo T, Balerao S, Sutton C, Johnson D, et al.
ACS Chem Neurosci . 2025 Feb; PMID: 40020199
The protein misfolding and aggregation of α-synuclein (α-Syn) into neurotoxic amyloids underlies the pathogenesis of neurodegenerative diseases such as Parkinson's disease (PD). Emerging evidence suggests that 4-phenylbutyrate (PBA) may play...
2.
Zhang Z, Patel R, Luo Z, Das C
J Mol Biol . 2024 Dec; 437(3):168917. PMID: 39694182
AMPylation is a post-translational modification (PTM) whereby adenosine monophosphate (AMP) from adenosine triphosphate (ATP) is transferred onto protein hydroxyl groups of serine, threonine, or tyrosine. Recently, an actin-dependent AMPylase namely...
3.
Razvi Y, Judge D, Martinez-Naharro A, Ioannou A, Venneri L, Patel R, et al.
Circ Heart Fail . 2024 Oct; 17(12):e012135. PMID: 39465243
No abstract available.
4.
Cook A, Cohen N, Patel R, South S, Ballantyne M
Cureus . 2024 Oct; 16(9):e69162. PMID: 39398739
Onychomycosis (OM) is a nail infection from various fungal species, representing a worldwide dermatologic health concern. The toenails are most often affected. Comorbid chronic health conditions and environmental and genetic...
5.
Porcari A, Masi A, Martinez-Naharro A, Razvi Y, Patel R, Ioannou A, et al.
JAMA Cardiol . 2024 Aug; 9(11):982-989. PMID: 39167388
Importance: Cardiac amyloid infiltration is the key determinant of survival in systemic light-chain (AL) amyloidosis. Current guidelines recommend early switching therapy in patients with a nonoptimal or suboptimal response regardless...
6.
Swissa E, Monsonego U, Yang L, Schori L, Kamintsky L, Mirloo S, et al.
Elife . 2024 Jul; 12. PMID: 39024007
Brain microvessels possess the unique properties of a blood-brain barrier (BBB), tightly regulating the passage of molecules from the blood to the brain neuropil and vice versa. In models of...
7.
Porcari A, Cappelli F, Nitsche C, Tomasoni D, Sinigiani G, Longhi S, et al.
J Am Coll Cardiol . 2024 Jun; 83(24):2411-2422. PMID: 38866445
Background: Transthyretin cardiomyopathy (ATTR-CM) was an exclusion criterion in randomized clinical trials of sodium-glucose cotransporter 2 inhibitors (SGLT2i). Objectives: This study sought to assess the effectiveness and tolerability of SGLT2i...
8.
Flint Z, Grannemann H, Baffour K, Koti N, Taylor E, Grier E, et al.
ACS Chem Neurosci . 2024 May; 15(11):2359-2371. PMID: 38728258
Elucidating the underlying principles of amyloid protein self-assembly at nanobio interfaces is extremely challenging due to the diversity in physicochemical properties of nanomaterials and their physical interactions with biological systems....
9.
Imhoff R, Patel R, Safdar M, Jones H, Pinto-Fernandez A, Vendrell I, et al.
J Med Chem . 2024 Mar; 67(6):4496-4524. PMID: 38488146
Dysregulation of the ubiquitin-proteasome systems is a hallmark of various disease states including neurodegenerative diseases and cancer. Ubiquitin C-terminal hydrolase L1 (UCHL1), a deubiquitinating enzyme, is expressed primarily in the...
10.
Merrill D, Craven J, Silvey S, Gouger D, Wang C, Patel R, et al.
J Intensive Care Med . 2024 Feb; 39(7):693-700. PMID: 38374621
Nontraumatic subarachnoid hemorrhage (SAH) can lead to poor neurologic outcomes, particularly when delayed cerebral ischemia (DCI) occurs. Maintenance of euvolemia following SAH is thought to reduce the risk of DCI....