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Risa Domoto

Explore the profile of Risa Domoto including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 123
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Recent Articles
1.
Miyamoto T, Domoto R, Sekiguchi F, Kamaguchi R, Nishimura R, Matsuno M, et al.
J Pharmacol Sci . 2022 Feb; 148(3):315-325. PMID: 35177211
Oxaliplatin often induces peripheral neuropathy, a dose-limiting adverse reaction, and in rare cases leads to sinusoidal obstruction syndrome. We thus conducted a retrospective cohort study to examine the relationship between...
2.
Domoto R, Sekiguchi F, Kamaguchi R, Iemura M, Yamanishi H, Tsubota M, et al.
J Pharmacol Sci . 2021 Dec; 148(1):156-161. PMID: 34924121
We examined the role of ATP and high mobility group box 1 (HMGB1) in paclitaxel-induced peripheral neuropathy (PIPN). PIPN in mice was prevented by HMGB1 neutralization, macrophage depletion, and P2X...
3.
Domoto R, Sekiguchi F, Tsubota M, Kawabata A
Cells . 2021 Aug; 10(8). PMID: 34440650
A neuroimmune crosstalk is involved in somatic and visceral pathological pain including inflammatory and neuropathic components. Apart from microglia essential for spinal and supraspinal pain processing, the interaction of bone...
4.
Sekiguchi F, Domoto R, Nakashima K, Yamasoba D, Yamanishi H, Tsubota M, et al.
Neuropharmacology . 2018 Sep; 141:201-213. PMID: 30179591
Given our recent evidence for the role of high mobility group box 1 (HMGB1) in chemotherapy-induced peripheral neuropathy (CIPN) in rats, we examined the origin of HMGB1 and the upstream...
5.
Yamasoba D, Tsubota M, Domoto R, Sekiguchi F, Nishikawa H, Liu K, et al.
J Pharmacol Sci . 2016 Feb; 130(2):139-42. PMID: 26883456
Nuclear HMGB1 that contains 3 cysteine residues is acetylated and secreted to the extracellular space, promoting inflammation via multiple molecules such as RAGE and TLR4. We thus evaluated and characterized...