Rina Okada
Overview
Explore the profile of Rina Okada including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
257
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Recent Articles
1.
Kosakamoto H, Sakuma C, Okada R, Miura M, Obata F
Sci Adv
. 2024 Aug;
10(35):eadn7167.
PMID: 39213345
Dietary protein intake modulates growth, reproduction, and longevity by stimulating amino acid (AA)-sensing pathways. Essential AAs are often considered as limiting nutrients during protein scarcity, and the role of dietary...
2.
Kosakamoto H, Obata F, Kuraishi J, Aikawa H, Okada R, Johnstone J, et al.
Nat Commun
. 2023 Dec;
14(1):7832.
PMID: 38052797
Methionine restriction (MetR) extends lifespan in various organisms, but its mechanistic understanding remains incomplete. Whether MetR during a specific period of adulthood increases lifespan is not known. In Drosophila, MetR...
3.
Rashid M, Ito T, Miya F, Shimojo D, Arimoto K, Onodera K, et al.
Sci Rep
. 2023 May;
13(1):8146.
PMID: 37231024
Pathophysiological analysis and drug discovery targeting human diseases require disease models that suitably recapitulate patient pathology. Disease-specific human induced pluripotent stem cells (hiPSCs) differentiated into affected cell types can potentially...
4.
Spratt S, Mizuguchi T, Akaboshi H, Kosakamoto H, Okada R, Obata F, et al.
Front Chem
. 2023 Apr;
11:1141920.
PMID: 37065821
Visualizing small individual biomolecules at subcellular resolution in live cells and tissues can provide valuable insights into metabolic activity in heterogeneous cells, but is challenging. Here, we used stimulated Raman...
5.
Matsusaki M, Okada R, Tanikawa Y, Kanemura S, Ito D, Lin Y, et al.
Biology (Basel)
. 2021 Nov;
10(11).
PMID: 34827105
P5 is one of protein disulfide isomerase family proteins (PDIs) involved in endoplasmic reticulum (ER) protein quality control that assists oxidative folding, inhibits protein aggregation, and regulates the unfolded protein...
6.
Onodera K, Shimojo D, Ishihara Y, Yano M, Miya F, Banno H, et al.
Mol Brain
. 2020 Feb;
13(1):18.
PMID: 32070397
Spinal bulbar muscular atrophy (SBMA) is an adult-onset, slowly progressive motor neuron disease caused by abnormal CAG repeat expansion in the androgen receptor (AR) gene. Although ligand (testosterone)-dependent mutant AR...
7.
Okada R, Onodera K, Ito T, Doyu M, Okano H, Okada Y
Neurosci Res
. 2020 Feb;
163:34-42.
PMID: 32014574
Human induced pluripotent stem cell (hiPSC)-derived neural cells provide valuable disease models for pathophysiological analysis and drug discovery for intractable neurodegenerative diseases. However, neural differentiation of hiPSCs requires a complex...
8.
Hatazawa Y, Yano Y, Okada R, Tanahashi T, Hayashi H, Hirano H, et al.
Infect Agent Cancer
. 2018 Feb;
13:7.
PMID: 29434654
Background: Hepatocellular carcinoma (HCC) can develop in patients who are negative for the hepatitis B surface antigen (HBsAg) in serum but positive for hepatitis B virus (HBV) DNA in the...
9.
Liang Y, Yano Y, Putri W, Mardian Y, Okada R, Tanahashi T, et al.
Mol Med Rep
. 2018 Feb;
17(4):5528-5537.
PMID: 29393485
Hepatitis B virus (HBV) polymerase gene is targeted by nucleos(t)ide analogues (NUC), but it is unclear how HBV quasispecies of whole genome changes during early period of NUC treatment. To...
10.
Yamamoto H, Okada R, Tanaka R, Unno K, Iguchi K
FEBS Open Bio
. 2017 Nov;
7(11):1784-1792.
PMID: 29123986
Small-cell lung carcinoma releases progalanin. The released progalanin is activated via a nonclassical processing pathway, being processed into an active form of galanin (1-20) by plasmin in extracellular components. Plasmin...