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Richard Weinshilboum

Explore the profile of Richard Weinshilboum including associated specialties, affiliations and a list of published articles. Areas
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Articles 95
Citations 2302
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Recent Articles
1.
Hoppe R, Winter S, Lo W, Michailidou K, Bolla M, Keeman R, et al.
NPJ Breast Cancer . 2025 Feb; 11(1):18. PMID: 39971965
The role of germline genetics in adjuvant aromatase inhibitor (AI) treatment efficacy in ER-positive breast cancer is poorly understood. We employed a two-stage candidate gene approach to examine associations between...
2.
Tuncturk M, Kushwaha S, Heider BS R, Heider R, Oesterle T, Weinshilboum R, et al.
Int J Neuropsychopharmacol . 2025 Jan; 28(2). PMID: 39831679
Opioid use disorder (OUD) affects over 40 million people worldwide, creating significant social and economic burdens. Medication for opioid use disorder (MOUD) is often considered the primary treatment approach for...
3.
Tang X, Prodduturi N, Thompson K, Weinshilboum R, OSullivan C, Boughey J, et al.
Nucleic Acids Res . 2024 Oct; 52(21):e99. PMID: 39445795
The OmicsFootPrint framework addresses the need for advanced multi-omics data analysis methodologies by transforming data into intuitive two-dimensional circular images and facilitating the interpretation of complex diseases. Utilizing deep neural...
4.
Li D, Pain O, Fabbri C, Wong W, Lo C, Ripke S, et al.
Transl Psychiatry . 2024 Aug; 14(1):350. PMID: 39217139
No abstract available.
5.
Li D, Pain O, Fabbri C, Wong W, Lo C, Ripke S, et al.
Transl Psychiatry . 2024 Jul; 14(1):296. PMID: 39025838
Cytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for antidepressant metabolism and polymorphisms of these genes have been determined to predict metabolite levels. Nonetheless, more evidence is needed to...
6.
Vazquez-Medina A, Turnbull M, James C, Cowart J, Lesser E, Carter R, et al.
Pharmacogenomics J . 2024 Jun; 24(4):19. PMID: 38890281
Nimodipine, an L-type cerebroselective calcium channel antagonist, is the only drug approved by the US Food and Drug Administration for the neuroprotection of patients with aneurysmal subarachnoid hemorrhage (aSAH). Four...
7.
Leon-Ferre R, Whitaker K, Suman V, Hoskin T, Giridhar K, Moore R, et al.
Breast Cancer Res . 2024 Jun; 26(1):97. PMID: 38858721
Background: Tumor immune infiltration and peripheral blood immune signatures have prognostic and predictive value in breast cancer. Whether distinct peripheral blood immune phenotypes are associated with response to neoadjuvant chemotherapy...
8.
Ho M, Zhang C, Moon I, Tuncturk M, Coombes B, Biernacka J, et al.
Transl Psychiatry . 2024 Mar; 14(1):165. PMID: 38531832
Alcohol use disorder (AUD) is the most prevalent substance use disorder worldwide. Acamprosate and naltrexone are anti-craving drugs used in AUD pharmacotherapy. However, molecular mechanisms underlying their anti-craving effect remain...
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10.
Li D, Pain O, Fabbri C, Wong W, Lo C, Ripke S, et al.
medRxiv . 2023 Jul; PMID: 37425775
Cytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for antidepressant metabolism and polymorphisms of these genes have been determined to predict metabolite levels. Nonetheless, more evidence is needed to...