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Richard Vytasek

Explore the profile of Richard Vytasek including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 87
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Recent Articles
1.
Zaloudikova M, Vytasek R, Raskova M, Vizek M, Uhlik J, Hampl V
Life Sci . 2019 Sep; 236:116864. PMID: 31518607
Aims: To elucidate the role of alveolar macrophages (AM) in the pathogenesis of hypoxic pulmonary hypertension (HPH), we tested the effects of sustained hypoxia on AM polarization and on the...
2.
Zaloudikova M, Eckhardt A, Vytasek R, Uhlik J, Novotny T, Bacakova L, et al.
Pulm Circ . 2019 Jun; 9(3):2045894019860747. PMID: 31187694
The development of hypoxic pulmonary hypertension is characterized by the structural remodeling of pulmonary arteries. However, the relationship between changes of arterial cells and the extracellular matrix remains unclear. We...
3.
Wilhelm J, Vytasek R, Uhlik J, Vajner L
Oxid Med Cell Longev . 2016 May; 2016:5057610. PMID: 27190574
Oxidative stress after birth led us to localize reactive oxygen and nitrogen species (RONS) production in the developing rat brain. Brains were assessed a day prenatally and on postnatal days...
4.
Wilhelm J, Ostadalova I, Vytasek R, Vajner L
Mol Cell Biochem . 2011 Jul; 358(1-2):215-20. PMID: 21769453
Reports describing production of reactive oxygen species in neonatal heart are missing. As lysyl oxidase is potentially important source of H(2)O(2), we studied its role during ontogenic development of rat...
5.
Vytasek R, Sedova L, Vilim V
BMC Musculoskelet Disord . 2010 May; 11:83. PMID: 20433772
Background: Levels of pentosidine (representative of advanced glycation end-products) in sera of patients with rheumatoid arthritis are increased when compared with sera of other diagnoses or healthy controls. These levels...
6.
Wilhelm J, Vytasek R, Ostadalova I, Vajner L
Mol Cell Biochem . 2009 Mar; 328(1-2):167-76. PMID: 19301099
Reactive oxygen species (ROS) play several biological roles. We investigated the applicability of fluorescent probes for their detection (i) in rabbit lens epithelial cells during ageing in culture, and (ii)...
7.
Wilhelm J, Fuksova H, Schwippelova Z, Vytasek R, Pichova A
Biofactors . 2006 Oct; 27(1-4):185-93. PMID: 17012774
Free radicals are considered the most important cause of cellular ageing. We have investigated ageing process in the yeast Saccharomyces cerevisiae. We have compared the wild type strain with the...
8.
Vajner L, Vytasek R, Lachmanova V, Uhlik J, Konradova V, Novotna J, et al.
Int J Exp Pathol . 2006 Sep; 87(5):383-91. PMID: 16965566
Chronic hypoxia results in pulmonary hypertension due to vasoconstriction and structural remodelling of peripheral lung blood vessels. We hypothesize that vascular remodelling is initiated in the walls of prealveolar pulmonary...
9.
Vilim V, Voburka Z, Vytasek R, Senolt L, Tchetverikov I, Kraus V, et al.
Clin Chim Acta . 2003 Feb; 328(1-2):59-69. PMID: 12559599
Background: Cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP 5) is one of the most promising serologic markers with regard to an ability to prognose development of osteoarthritis (OA). Our aim was...