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Richard Troughton

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Articles 77
Citations 1273
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Recent Articles
1.
Thiessen N, Pickering J, Kellner C, Haller P, Lehmacher J, Toprak B, et al.
Can J Cardiol . 2025 Feb; PMID: 40021054
Background: A limitation of diagnostic algorithms in suspected myocardial infarction (MI) is the requirement for assay-specific high-sensitivity cardiac troponin (hs-cTn) cut-off concentrations and change criteria. We sought to evaluate a...
2.
Matsumoto S, Jhund P, Henderson A, Bauersachs J, Claggett B, Desai A, et al.
J Am Coll Cardiol . 2025 Jan; 85(2):173-185. PMID: 39814476
Background: An initial decline in estimated glomerular filtration rate (eGFR) often leads to reluctance to continue life-saving therapies in patients with heart failure (HF). Objectives: The goal of this study...
3.
Lim E, Jardine D, Frampton C, Pemberton C, Troughton R, Roake J, et al.
J Vasc Res . 2024 Dec; 1-8. PMID: 39733774
Introduction: Control of blood pressure following acute type B aortic dissection usually requires sympatholytic antihypertensive medication. Although sympathetic nerve activity is central to blood pressure control, its role in the...
4.
Zhou K, Alemayehu W, Rathwell S, McAlister F, Ross H, Escobedo J, et al.
Am Heart J . 2024 Dec; 281:49-58. PMID: 39643096
Background: SODIUM-HF was a large clinical trial testing dietary sodium restriction compared to usual care in patients with heart failure that showed no reduction in clinical events. It has been...
5.
Solomon S, McMurray J, Vaduganathan M, Claggett B, Jhund P, Desai A, et al.
N Engl J Med . 2024 Sep; 391(16):1475-1485. PMID: 39225278
Background: Steroidal mineralocorticoid receptor antagonists reduce morbidity and mortality among patients with heart failure and reduced ejection fraction, but their efficacy in those with heart failure and mildly reduced or...
6.
Deep A, Chan C, Adamson P, Troughton R, Woodcock E
CASE (Phila) . 2024 May; 8(4):303-307. PMID: 38765627
No abstract available.
7.
Solomon S, Ostrominski J, Vaduganathan M, Claggett B, Jhund P, Desai A, et al.
Eur J Heart Fail . 2024 May; 26(6):1334-1346. PMID: 38733212
Aims: To describe the baseline characteristics of participants in the FINEARTS-HF trial, contextualized with prior trials including patients with heart failure (HF) with mildly reduced and preserved ejection fraction (HFmrEF/HFpEF)....
8.
Chew-Harris J, Frampton C, Greer C, Appleby S, Pickering J, Kuan W, et al.
Int J Cardiol . 2024 Apr; 406:132071. PMID: 38643805
Aims: The performance of circulating soluble urokinase plasminogen activator receptor (suPAR) for predicting the composite endpoint of subsequent heart failure (HF) hospitalisation and/or death at 1 year was assessed in...
9.
Lindenfeld J, Costanzo M, Zile M, Ducharme A, Troughton R, Maisel A, et al.
J Am Coll Cardiol . 2024 Feb; 83(6):682-694. PMID: 38325994
Background: Trials evaluating implantable hemodynamic monitors to manage patients with heart failure (HF) have shown reductions in HF hospitalizations but not mortality. Prior meta-analyses assessing mortality have been limited in...
10.
Appleby S, Frampton C, Holdaway M, Chew-Harris J, Liew O, Chong J, et al.
Front Cardiovasc Med . 2024 Jan; 10:1195082. PMID: 38259307
Objectives: In dyspneic patients with atrial fibrillation (AF) or obesity, the diagnostic performance of NT-proBNP for acute heart failure is reduced. We evaluated the erythroblast derived protein erythroferrone (ERFE) as...