Richard Schlegel
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Explore the profile of Richard Schlegel including associated specialties, affiliations and a list of published articles.
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94
Citations
3318
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Recent Articles
1.
Daneshdoust D, Luo M, Li Z, Mo X, Alothman S, Kallakury B, et al.
Cells
. 2023 Oct;
12(19).
PMID: 37830602
Preclinical in vitro models play an important role in studying cancer cell biology and facilitating translational research, especially in the identification of drug targets and drug discovery studies. This is...
2.
Xiao J, Sharma U, Arab A, Miglani S, Bhalla S, Suguru S, et al.
Cancers (Basel)
. 2023 Mar;
15(6).
PMID: 36980717
Circulating tumor cells (CTCs), a population of cancer cells that represent the seeds of metastatic nodules, are a promising model system for studying metastasis. However, the expansion of patient-derived CTCs...
3.
Wang A, Zhou D, Krawczyk E, Li T, Simic V, Lu J, et al.
J Med Virol
. 2023 Mar;
95(4):e28681.
PMID: 36929719
Cervical cancer is the most frequent malignancy of the female genital tract and is associated with persistent infection of the uterine cervix with high-risk human papillomaviruses (HPV). The two HPV...
4.
Zhou D, Wang A, Maxwell S, Schlegel R, Yuan H
Viruses
. 2022 Dec;
14(12).
PMID: 36560679
Canine ocular papillomas occur on the haired skin of eyelids, conjunctival epithelium, and rarely on the cornea. Using PCR typing assays with canine papillomavirus type-specific primer sets, our study confirmed...
5.
Xiao J, McGill J, Nasir A, Lekan A, Johnson B, Wilkins D, et al.
Mol Biomed
. 2022 May;
3(1):16.
PMID: 35614362
Cancer metastasis is the primary cause of the high mortality rate among human cancers. Efforts to identify therapeutic agents targeting cancer metastasis frequently fail to demonstrate efficacy in clinical trials...
6.
Sudarshan S, Schlegel R, Liu X
J Med Virol
. 2022 May;
94(9):4565-4575.
PMID: 35509176
The high-risk alpha human papillomaviruses (HPVs) are responsible for 99% of cervical cancers. While the biological functions of the HPV E6 and E7 oncoproteins are well-characterized, the function of E5...
7.
Miller J, Dakic A, Spurgeon M, Saenz F, Kallakury B, Zhao B, et al.
J Med Virol
. 2022 Apr;
94(8):3962-3977.
PMID: 35437795
The high-risk human papillomaviruses (HPV-16, -18) are critical etiologic agents in human malignancy, most importantly in cervical cancer. These oncogenic viruses encode the E6 and E7 proteins that are uniformly...
8.
Xiao J, Pohlmann P, Isaacs C, Weinberg B, He A, Schlegel R, et al.
Biomedicines
. 2021 Sep;
9(9).
PMID: 34572297
Circulating tumor cells (CTCs) are single cells or clusters of cells within the circulatory system of a cancer patient. While most CTCs will perish, a small proportion will proceed to...
9.
Xiao J, McGill J, Stanton K, Kassner J, Choudhury S, Schlegel R, et al.
Cancers (Basel)
. 2020 Oct;
12(10).
PMID: 32998338
Circulating tumor cells (CTCs) represent a unique population of cells that can be used to investigate the mechanistic underpinnings of metastasis. Unfortunately, current technologies designed for the isolation and capture...
10.
Casciano J, Perry C, Cohen-Nowak A, Miller K, Vande Voorde J, Zhang Q, et al.
Br J Cancer
. 2020 Jan;
122(6):868-884.
PMID: 31942031
Background: Recent studies have suggested that fatty acid oxidation (FAO) is a key metabolic pathway for the growth of triple negative breast cancers (TNBCs), particularly those that have high expression...