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Richard R Spaete

Explore the profile of Richard R Spaete including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Williams J, Edwards K, Weinberg G, Griffin M, Hall C, Zhu Y, et al.
J Infect Dis . 2010 May; 201(12):1890-8. PMID: 20446850
Background: Human metapneumovirus (HMPV) is a leading cause of acute respiratory illness (ARI) in children. Population-based incidence rates and comprehensive clinical characterizations of disease have not been established. Methods: We...
2.
Yang C, Wang C, Tollefson S, Piyaratna R, Lintao L, Chu M, et al.
Virol J . 2009 Sep; 6:138. PMID: 19740442
Background: Human metapneumovirus (HMPV) is an important cause of acute respiratory illness in children. We examined the diversity and molecular evolution of HMPV using 85 full-length F (fusion) gene sequences...
3.
Tang R, Spaete R, Thompson M, MacPhail M, Guzzetta J, Ryan P, et al.
Vaccine . 2008 Sep; 26(50):6373-82. PMID: 18822334
MEDI-534 is a bivalent live attenuated vaccine candidate against human respiratory syncytial virus (hRSV) and human parainfluenza virus type 3 (hPIV3) that was previously shown to be immunogenic and to...
4.
Schickli J, Kaur J, MacPhail M, Guzzetta J, Spaete R, Tang R
Virol J . 2008 Jun; 5:69. PMID: 18519001
Background: Human metapneumovirus (hMPV) infection can cause acute lower respiratory tract illness in infants, the immunocompromised, and the elderly. Currently there are no licensed preventative measures for hMPV infections. Using...
5.
Heineman T, Schleiss M, Bernstein D, Spaete R, Yan L, Duke G, et al.
J Infect Dis . 2006 Apr; 193(10):1350-60. PMID: 16619181
Background: Human cytomegalovirus (HCMV) infection acquired in utero often results in severe consequences, including mental retardation and deafness. Although not evaluated for this indication, live attenuated HCMV vaccines based on...
6.
Buonagurio D, Bechert T, Yang C, Shutyak L, DArco G, Kazachkov Y, et al.
Vaccine . 2006 Jan; 24(12):2151-60. PMID: 16413951
FluMist is a live-attenuated, trivalent influenza vaccine (LAIV) recently approved for intranasal administration. To demonstrate genetic stability during manufacture of the vaccine viruses in LAIV and a similar vaccine in...
7.
Williams J, Wang C, Yang C, Tollefson S, House F, Heck J, et al.
J Infect Dis . 2006 Jan; 193(3):387-95. PMID: 16388486
Background: The role that human metapneumovirus (hMPV) plays in the etiology of upper respiratory tract infections (URIs) in children over a period of many years has not been evaluated previously....
8.
Schickli J, Kaur J, Ulbrandt N, Spaete R, Tang R
J Virol . 2005 Jul; 79(16):10678-89. PMID: 16051860
Human metapneumovirus (hMPV), a recently described paramyxovirus, is a major etiological agent for lower respiratory tract disease in young children that can manifest with severe cough, bronchiolitis, and pneumonia. The...
9.
Prichard M, Kaiwar R, Jackman W, Quenelle D, Collins D, Kern E, et al.
Vaccine . 2005 Jun; 23(46-47):5424-31. PMID: 15950327
An attenuated recombinant herpes simplex virus type 2 (HSV-2), designated as AD472, was constructed by deleting both copies of the gamma(1)34.5 gene, UL55-56, UL43.5, and the US10-12 region from HSV-2...
10.
Tang R, Mahmood K, MacPhail M, Guzzetta J, Haller A, Liu H, et al.
Vaccine . 2005 Feb; 23(14):1657-67. PMID: 15705469
Human metapneumovirus (hMPV) infection causes respiratory tract disease similar to that observed during human respiratory syncytial virus infection (hRSV). hMPV infections have been reported across the entire age spectrum although...