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Richard Langford

Explore the profile of Richard Langford including associated specialties, affiliations and a list of published articles. Areas
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Citations 549
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Recent Articles
1.
Viscusi E, Langford R, Morte A, Vaque A, Cebrecos J, Sust M, et al.
Pain Ther . 2024 Sep; 13(6):1617-1631. PMID: 39316284
Introduction: Multi-modal analgesia is desirable for the management of acute pain since it can provide effective pain relief at lower doses, thereby aiding tolerability. Co-crystal of tramadol-celecoxib (CTC) provides effective...
2.
Langford R, Viscusi E, Morte A, Cebrecos J, Sust M, Gimenez-Arnau J, et al.
Drugs R D . 2024 Jun; 24(2):239-252. PMID: 38874739
Background And Objectives: New acute pain medications are needed that provide effective analgesia while minimizing side effects and opioid exposure. Clinical trials of co-crystal of tramadol-celecoxib (CTC) have demonstrated an...
3.
Langford R, Margarit C, Morte A, Cebrecos J, Sust M, Ortiz E, et al.
Curr Med Res Opin . 2024 Jan; 40(3):455-468. PMID: 38205948
Objective: This narrative review aims to provide a clinical perspective on the potential role of co-crystal of tramadol-celecoxib (CTC) in the management of acute moderate-to-severe pain by synthesizing the available...
4.
Langford R, Pogatzki-Zahn E, Morte A, Sust M, Cebrecos J, Vaque A, et al.
Adv Ther . 2024 Jan; 41(3):1025-1045. PMID: 38183526
Introduction: Co-crystal of tramadol-celecoxib (CTC) is the first analgesic co-crystal for acute pain. This completed phase 3 multicenter, double-blind trial assessed the efficacy and safety/tolerability of CTC in comparison with...
5.
Langford R, Morte A, Sust M, Cebrecos J, Vaque A, Ortiz E, et al.
Eur J Pain . 2022 Aug; 26(10):2083-2096. PMID: 35974668
Background: STARDOM2 is a randomized, double-blind, phase 3 trial evaluating the efficacy and safety of co-crystal of tramadol-celecoxib (CTC)-a first-in-class analgesic co-crystal comprising racemic tramadol hydrochloride and celecoxib in a...
6.
Bourke J, Wodehouse T, Clark L, Constantinou E, Kidd B, Langford R, et al.
J Psychosom Res . 2021 Oct; 150:110624. PMID: 34600309
Introduction: Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are both complex conditions that are challenging to treat. This may be related to an incomplete understanding of their pathophysiology, itself obfuscated...
7.
Berenbaum F, Langford R, Perrot S, Miki K, Blanco F, Yamabe T, et al.
Eur J Pain . 2021 Mar; 25(7):1525-1539. PMID: 33728717
Background: To evaluate if early improvements in pain and function with subcutaneous tanezumab are meaningful and sustained over 24 weeks. Methods: Patients with moderate-to-severe osteoarthritis (hip or knee) in Europe...
8.
Clouse K, Phillips T, Camlin C, Noholoza S, Mogoba P, Naidoo J, et al.
Trials . 2020 Mar; 21(1):258. PMID: 32164771
Background: South Africa is home to the world's largest antiretroviral therapy program but sustaining engagement along the HIV care continuum has proven challenging in the country and throughout the wider...
9.
Wodehouse T, Demopoulos M, Petty R, Miraki-Moud F, Belhaj A, Husband M, et al.
Pain . 2019 Aug; 160(12):2691-2698. PMID: 31433352
Endogenous opioid peptides and exogenous opioids modulate immune function, and animal and human studies have shown that some have a depressant immunomodulatory effect. This is potentially of high clinical significance,...
10.
Anwar S, Cooper J, Rahman J, Sharma C, Langford R
Anesthesiology . 2019 Jun; 131(1):119-131. PMID: 31149930
Background: Persistent postsurgical pain is common and affects quality of life. The hypothesis was that use of pregabalin and ketamine would prevent persistent pain after cardiac surgery. Methods: This randomized,...