Richard J Lessells
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Explore the profile of Richard J Lessells including associated specialties, affiliations and a list of published articles.
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78
Citations
5194
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Recent Articles
21.
Khan K, Karim F, Ganga Y, Bernstein M, Jule Z, Reedoy K, et al.
Nat Commun
. 2022 Aug;
13(1):4686.
PMID: 35948557
SARS-CoV-2 Omicron (B.1.1.529) BA.4 and BA.5 sub-lineages, first detected in South Africa, have changes relative to Omicron BA.1 including substitutions in the spike receptor binding domain. Here we isolated live...
22.
Maponga T, Jeffries M, Tegally H, Sutherland A, Wilkinson E, Lessells R, et al.
Clin Infect Dis
. 2022 Jul;
76(3):e522-e525.
PMID: 35793242
A 22-year-old woman with uncontrolled advanced human immunodeficiency virus (HIV) infection was persistently infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) beta variant for 9 months, the virus accumulating...
23.
Tegally H, Moir M, Everatt J, Giovanetti M, Scheepers C, Wilkinson E, et al.
Nat Med
. 2022 Jun;
28(9):1785-1790.
PMID: 35760080
Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's fourth Coronavirus Disease 2019 (COVID-19) wave. We...
24.
Khan K, Karim F, Cele S, Reedoy K, San J, Lustig G, et al.
Nature
. 2022 May;
607(7918):356-359.
PMID: 35523247
The extent to which Omicron infection, with or without previous vaccination, elicits protection against the previously dominant Delta (B.1.617.2) variant is unclear. Here we measured the neutralization capacity against variants...
25.
Tshiabuila D, Giandhari J, Pillay S, Ramphal U, Ramphal Y, Maharaj A, et al.
BMC Genomics
. 2022 Apr;
23(1):319.
PMID: 35459088
Background: Over 4 million SARS-CoV-2 genomes have been sequenced globally in the past 2 years. This has been crucial in elucidating transmission chains within communities, the development of new diagnostic...
26.
Moosa M, Lessells R
N Engl J Med
. 2022 Mar;
386(12):1179-1181.
PMID: 35320648
No abstract available.
27.
Singh L, San J, Tegally H, Brzoska P, Anyaneji U, Wilkinson E, et al.
Microb Genom
. 2022 Mar;
8(3).
PMID: 35294336
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is adaptively evolving to ensure its persistence within human hosts. It is therefore necessary to continuously monitor the emergence and prevalence of novel...
28.
Cele S, Karim F, Lustig G, San J, Hermanus T, Tegally H, et al.
Cell Host Microbe
. 2022 Feb;
30(2):154-162.e5.
PMID: 35120605
Characterizing SARS-CoV-2 evolution in specific geographies may help predict properties of the variants that come from these regions. We mapped neutralization of a SARS-CoV-2 strain that evolved over 6 months...
29.
Viana R, Moyo S, Amoako D, Tegally H, Scheepers C, Althaus C, et al.
Nature
. 2022 Jan;
603(7902):679-686.
PMID: 35042229
The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were...
30.
Cele S, Jackson L, Khoury D, Khan K, Moyo-Gwete T, Tegally H, et al.
Nature
. 2022 Jan;
602(7898):654-656.
PMID: 35016196
The emergence of the SARS-CoV-2 variant of concern Omicron (Pango lineage B.1.1.529), first identified in Botswana and South Africa, may compromise vaccine effectiveness and lead to re-infections. Here we investigated...