Richard J Kascsak
Overview
Explore the profile of Richard J Kascsak including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
448
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pankiewicz J, Sanchez S, Kirshenbaum K, Kascsak R, Kascsak R, Sadowski M
Mol Neurobiol
. 2018 Jul;
56(3):2073-2091.
PMID: 29987703
PrP is an infectious and disease-specific conformer of the prion protein, which accumulation in the CNS underlies the pathology of prion diseases. PrP replicates by binding to the cellular conformer...
2.
Cho I, Spinner D, Kascsak R, Meeker H, Kim B, Park S, et al.
Viral Immunol
. 2013 May;
26(3):192-200.
PMID: 23656168
Lymphoid organs play an important role in prion disease development and progression. While the role of lymphoid organs and changes in immune-related genes have been extensively investigated in scrapie-infected animals,...
3.
Kim B, Spinner D, Kascsak R, Park S, Cho I, Schuller-Levis G, et al.
J Drugs Dermatol
. 2013 May;
12(5):551-7.
PMID: 23652950
Taurine plays an important role in brain and retinal development, and has an antiinflammatory and antioxidant function. Taurine chloramine (Tau-Cl) is produced in polymorphonuclear leukocytes via the myeloperoxidase/halide system. We...
4.
Chung E, Ji Y, Sun Y, Kascsak R, Kascsak R, Mehta P, et al.
BMC Neurosci
. 2010 Oct;
11:130.
PMID: 20946660
Background: Alzheimer's Disease (AD) is the most common of the conformational neurodegenerative disorders characterized by the conversion of a normal biological protein into a β-sheet-rich pathological isoform. In AD the...
5.
Sadowski M, Pankiewicz J, Prelli F, Scholtzova H, Spinner D, Kascsak R, et al.
Neurobiol Dis
. 2009 Apr;
34(2):267-78.
PMID: 19385058
The pathogenesis of prion diseases is related to conformational transformation of cellular prion protein (PrP(C)) into a toxic, infectious, and self-replicating conformer termed PrP(Sc). Following extracerebral inoculation, the replication of...
6.
Scholtzova H, Kascsak R, Bates K, Boutajangout A, Kerr D, Meeker H, et al.
J Neurosci
. 2009 Feb;
29(6):1846-54.
PMID: 19211891
The pathogenesis of Alzheimer's disease (AD) is thought to be related to the accumulation of amyloid beta (Abeta) in amyloid deposits and toxic oligomeric species. Immunomodulation is emerging as an...
7.
Spinner D, Cho I, Park S, Kim J, Meeker H, Ye X, et al.
J Virol
. 2008 Aug;
82(21):10701-8.
PMID: 18715916
Prion diseases such as scrapie involve the accumulation of disease-specific prion protein, PrP(Sc), in the brain. Toll-like receptors (TLRs) are a family of proteins that recognize microbial constituents and are...
8.
Gregori L, Gray B, Rose E, Spinner D, Kascsak R, Rohwer R
J Virol Methods
. 2008 Mar;
149(2):251-9.
PMID: 18339433
Transmissible spongiform encephalopathies can be transmitted by blood transfusion. The risk of spreading the disease among the human population could be mitigated with the implementation of a blood screening assay....
9.
Spinner D, Kascsak R, LaFauci G, Meeker H, Ye X, Flory M, et al.
J Leukoc Biol
. 2007 Mar;
81(6):1374-85.
PMID: 17379700
Prion diseases are characterized by conversion of the cellular prion protein (PrP(C)) to a protease-resistant conformer, the srapie form of PrP (PrP(Sc)). Humoral immune responses to nondenatured forms of PrP(Sc)...
10.
Pankiewicz J, Prelli F, Sy M, Kascsak R, Kascsak R, Spinner D, et al.
Eur J Neurosci
. 2006 Jul;
23(10):2635-47.
PMID: 16817866
Prion diseases are transmissible and invariably fatal neurodegenerative disorders associated with a conformational transformation of the cellular prion protein (PrP(C)) into a self-replicating and proteinase K (PK)-resistant conformer, scrapie PrP...