Richard J Fish
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Explore the profile of Richard J Fish including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
773
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Recent Articles
1.
Dobson D, Fish R, de Vries P, Morrison A, Neerman-Arbez M, Wolberg A
Thromb Res
. 2024 Aug;
242:109134.
PMID: 39216273
The plasma protein fibrinogen is encoded by 3 structural genes (FGA, FGB, and FGG) that are transcribed to mRNA, spliced, and translated to 3 polypeptide chains (Aα, Bβ, and γ,...
2.
Griffin M, Dahlgren A, Nagaswami C, Litvinov R, Keeler K, Madenjian C, et al.
J Thromb Haemost
. 2023 Dec;
22(4):1056-1068.
PMID: 38160724
Background: Blood clots are primarily composed of red blood cells (RBCs), platelets/thrombocytes, and fibrin. Despite the similarities observed between mammals and zebrafish, the composition of fish thrombi is not as...
3.
Li L, Krasnykov K, Homolka D, Gos P, Mendel M, Fish R, et al.
Mol Cell
. 2022 Mar;
82(9):1678-1690.e12.
PMID: 35305312
The functional consequence of N-methyladenosine (mA) RNA modification is mediated by "reader" proteins of the YTH family. YTH domain-containing 2 (YTHDC2) is essential for mammalian fertility, but its molecular function...
4.
Fish R, Freire C, Di Sanza C, Neerman-Arbez M
Int J Mol Sci
. 2021 Jan;
22(2).
PMID: 33440782
Venous thrombosis occurs in patients with quantitative and qualitative fibrinogen disorders. Injury-induced thrombosis in zebrafish larvae has been used to model human coagulopathies. We aimed to determine whether zebrafish models...
5.
Vilar R, Lukowski S, Garieri M, Di Sanza C, Neerman-Arbez M, Fish R
Thromb Haemost
. 2020 Dec;
121(4):433-448.
PMID: 33302304
Thrombosis is a leading cause of morbidity and mortality. Fibrinogen, the soluble substrate for fibrin-based clotting, has a central role in haemostasis and thrombosis and its plasma concentration correlates with...
6.
Freire C, Fish R, Vilar R, Di Sanza C, Grzegorski S, Richter C, et al.
Blood Adv
. 2020 Nov;
4(21):5480-5491.
PMID: 33166405
Plasma fibrinogen molecules comprise 2 copies of Aα, Bβ, and γ chains folded into a hexameric protein. A minor fibrinogen isoform with an extended Aα chain (AαE) is more abundant...
7.
Garcia A, Dunoyer-Geindre S, Fish R, Neerman-Arbez M, Reny J, Fontana P
Thromb Haemost
. 2020 Oct;
121(4):409-421.
PMID: 33124028
MicroRNAs (miRNAs) are small noncoding RNAs modulating protein production. They are key players in regulation of cell function and are considered as biomarkers in several diseases. The identification of the...
8.
Zapilko V, Fish R, Garcia A, Reny J, Dunoyer-Geindre S, Lecompte T, et al.
Platelets
. 2020 Jun;
31(6):746-755.
PMID: 32529909
Circulating microRNA (miRNA) expression profiles correlate with platelet reactivity. MiR-126 is a promising candidates in this regard. We generated a transgenic zebrafish line with thrombocyte-specific overexpression of miR-126. Laser injury...
9.
Vilar R, Fish R, Casini A, Neerman-Arbez M
Haematologica
. 2020 Jan;
105(2):284-296.
PMID: 31949010
Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 days....
10.
Meta E, Imhof B, Ropraz P, Fish R, Brullo C, Bruno O, et al.
Oncotarget
. 2018 Jan;
8(64):108195-108212.
PMID: 29296234
The limitation of targeting VEGF/VEGFR2 signalling to stop angiogenesis in cancer therapy has been blamed on re-activation of alternative receptor tyrosine kinases by compensatory angiogenic factors. Targeting MAPK and PI3K...