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Richard J Bauer

Explore the profile of Richard J Bauer including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 634
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Recent Articles
1.
Fiedler M, Off A, Gartner A, Brockhoff G, Eichberger J, Gottsauner M, et al.
Head Neck . 2024 Oct; 47(3):822-831. PMID: 39462876
Background: This study aimed to explore the disparities in PD-1 and PD-L1 expression among oral squamous cell carcinomas (OSCCs) in individuals categorized as never-smokers/never-drinkers versus smokers/drinkers. Methods: Immunohistochemical staining for...
2.
Rubenich D, Domagalski J, Gentil G, Eichberger J, Fiedler M, Weber F, et al.
J Extracell Vesicles . 2024 Jul; 13(7):e12480. PMID: 38978304
Head and neck squamous cell carcinoma (HNSCC) is a global cancer burden with a 5-year overall survival rate of around 50%, stagnant for decades. A tumour-induced immunosuppressive microenvironment contributes to...
3.
Lindner G, Walter A, Magnus C, Rosenhammer K, Holoborodko B, Koch V, et al.
Immunology . 2024 Mar; 172(2):279-294. PMID: 38444199
In 2015, the oncolytic herpes simplex virus 1 (HSV-1) T-VEC (talimogene laherparepvec) was approved for intratumoral injection in non-resectable malignant melanoma. To determine whether viral replication is required for oncolytic...
4.
Schulz D, Feulner L, Santos Rubenich D, Heimer S, Rohrmuller S, Reinders Y, et al.
Mol Oncol . 2023 Dec; 18(2):431-452. PMID: 38103190
The programmed cell death 1 ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) axis is primarily associated with immunosuppression in cytotoxic T lymphocytes (CTLs). However, mounting evidence is supporting the...
5.
Wang C, Stockl S, Pattappa G, Schulz D, Hofmann K, Ilic J, et al.
Biomedicines . 2023 Oct; 11(10). PMID: 37893177
In orthopedics, musculoskeletal disorders, i.e., non-union of bone fractures or osteoporosis, can have common histories and symptoms related to pathological hypoxic conditions induced by aging, trauma or metabolic disorders. Here,...
6.
Eichberger J, Froschhammer D, Schulz D, Scholz K, Federlin M, Ebensberger H, et al.
Int J Mol Sci . 2023 Oct; 24(19). PMID: 37833873
In recent research, the tumor microenvironment has been shown to attract mesenchymal stromal cells (MSCs), which is of particular interest due to its implications for cancer progression. The study focused...
7.
Fiedler M, Off A, Eichberger J, Spoerl S, Schuderer J, Taxis J, et al.
Cancers (Basel) . 2023 Jun; 15(10). PMID: 37345025
The aim of this study was to investigate the clinical, histopathologic, and immunologic differences of oral squamous cell carcinoma of never-smokers/never-drinkers and smokers/drinkers. Immunohistochemical staining for CD4, CD8, FoxP3, CD1a,...
8.
Waltera A, Schulz D, Schaefer N, Stoeckl S, Pion E, Haerteis S, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674806
Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor cell-derived signals, such as inflammatory cytokines and growth factors. As a result, the inflammatory tumor microenvironment may lead...
9.
Ludwig N, Yerneni S, Azambuja J, Pietrowska M, Widlak P, Hinck C, et al.
J Extracell Vesicles . 2022 Dec; 11(12):e12294. PMID: 36537293
Transforming growth factor β (TGFβ) is a major component of tumor-derived small extracellular vesicles (TEX) in cancer patients. Mechanisms utilized by TGFβ TEX to promote tumor growth and pro-tumor activities...
10.
Schulz D, Wetzel M, Eichberger J, Piendl G, Brockhoff G, Wege A, et al.
Int J Mol Sci . 2021 Dec; 22(23). PMID: 34884892
The expression of PD-L1 by tumor cells is mainly associated with its immunosuppressive effect. In fact, PD-1/PD-L1 immune checkpoint inhibitors demonstrated remarkable effects in advanced cancer patients including HNSCC. In...