Richard Grundy
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Explore the profile of Richard Grundy including associated specialties, affiliations and a list of published articles.
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52
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1905
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Recent Articles
1.
Cognitive Outcomes in Children Treated for Ependymoma Diagnosed Under 36 Months: A Systematic Review
Thomas S, Morley E, Ritzmann T, Clayton C, Powers K, Airdrie J, et al.
Pediatr Blood Cancer
. 2025 Feb;
:e31588.
PMID: 39937086
It is crucial to understand the morbidity associated with treatments for young children with ependymoma given this is a high incidence age group also known to be at risk of...
2.
Butler A, Meijer L, Liu J, Chohan M, Jalloh I, Macarthur D, et al.
Childs Nerv Syst
. 2023 Mar;
39(6):1537-1544.
PMID: 36949251
Purpose: The aim of the project was to evaluate intra-CSF etoposide administration in a palliative setting for children and young people with relapsed/refractory central nervous system (CNS) tumours, with the...
3.
Powell S, Withey S, Sun Y, Grist J, Novak J, MacPherson L, et al.
Br J Radiol
. 2023 Feb;
96(1145):20201465.
PMID: 36802769
Objective: Investigate the performance of qualitative review (QR) for assessing dynamic susceptibility contrast (DSC-) MRI data quality in paediatric normal brain and develop an automated alternative to QR. Methods: 1027...
4.
Thomas S, Embry L, Walsh K, Bull K, Grundy R, Kennedy C, et al.
Pediatr Blood Cancer
. 2023 Feb;
70(5):e30171.
PMID: 36734371
The importance of measuring quality of survival within paediatric oncology trials is increasingly recognised. However, capturing neuropsychological outcomes and other aspects of quality of survival in the context of large...
5.
Milne P, Bomken S, Slater O, Kumar A, Nelson A, Roy S, et al.
Blood Adv
. 2022 Sep;
7(10):2171-2176.
PMID: 36112425
Most children with high-risk Langerhans cell histiocytosis (LCH) have BRAFV600E mutation. BRAFV600E alleles are detectable in myeloid mononuclear cells at diagnosis but it is not known if the cellular distribution...
6.
Nohtani M, Vrzalikova K, Ibrahim M, Powell J, Fennell E, Morgan S, et al.
Cancers (Basel)
. 2022 Sep;
14(17).
PMID: 36077832
In this study, we have re-evaluated how EBV status influences clinical outcome. To accomplish this, we performed a literature review of all studies that have reported the effect of EBV...
7.
Lindsay H, Massimino M, Avula S, Stivaros S, Grundy R, Metrock K, et al.
Lancet Oncol
. 2022 Jul;
23(8):e393-e401.
PMID: 35901835
Response criteria for paediatric intracranial ependymoma vary historically and across different international cooperative groups. The Response Assessment in the Pediatric Neuro-Oncology (RAPNO) working group, consisting of an international panel of...
8.
Bouzinab K, Summers H, Zhang J, Stevens M, Moody C, Turyanska L, et al.
Cancer Drug Resist
. 2022 May;
2(4):1018-1031.
PMID: 35582280
Glioblastoma multiforme is the most common and lethal brain tumour-type. The current standard of care includes Temozolomide (TMZ) chemotherapy. However, inherent and acquired resistance to TMZ thwart successful treatment. The...
9.
Withey S, MacPherson L, Oates A, Powell S, Novak J, Abernethy L, et al.
Pediatr Radiol
. 2022 Mar;
52(6):1134-1149.
PMID: 35290489
Background: Relative cerebral blood volume (rCBV) measured using dynamic susceptibility-contrast MRI can differentiate between low- and high-grade pediatric brain tumors. Multicenter studies are required for translation into clinical practice. Objective:...
10.
Branter J, Estevez-Cebrero M, Diksin M, Griffin M, Castellanos-Uribe M, May S, et al.
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216098
The lack of treatment options for high-grade brain tumors has led to searches for alternative therapeutic modalities. Electrical field therapy is one such area. The Optune™ system is an FDA-approved...