Richard C Zieren
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Explore the profile of Richard C Zieren including associated specialties, affiliations and a list of published articles.
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8
Citations
231
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Recent Articles
1.
Zieren R, Zondervan P, Pienta K, Bex A, de Reijke T, Bins A
Nat Rev Urol
. 2023 Sep;
21(3):133-157.
PMID: 37758847
The clinical presentation of renal cell cancer (RCC) is shifting towards incidental and early detection, creating new challenges in RCC diagnosis. Overtreatment might be reduced with the development of new...
2.
Kuczler M, Zieren R, Dong L, de Reijke T, Pienta K, Amend S
Urology
. 2021 Nov;
160:87-93.
PMID: 34793840
Objective: To propose EV-derived mRNA as a potential diagnostic biomarker detecting the presence of clear cell renal cell carcinoma (ccRCC). There is currently no kidney cancer specific screening or diagnostic...
3.
Zieren R, Dong L, Clark D, Kuczler M, Horie K, Moreno L, et al.
Med Oncol
. 2021 Jul;
38(9):105.
PMID: 34331598
Renal cell carcinoma (RCC) accounts for over 400,000 new cases and 175,000 deaths annually. Diagnostic RCC biomarkers may prevent overtreatment in patients with early disease. Extracellular vesicles (EVs) are a...
4.
Dong L, Huang C, Johnson E, Yang L, Zieren R, Horie K, et al.
Anal Chem
. 2021 Feb;
93(8):3717-3725.
PMID: 33596381
Extracellular vesicles (EVs) are nano-sized lipid bilayer encapsulated particles with a molecular cargo that appears to play important roles within the human body, such as in cell-to-cell communication. Unraveling the...
5.
Dong L, Zieren R, Horie K, Kim C, Mallick E, Jing Y, et al.
J Extracell Vesicles
. 2021 Jan;
10(2):e12044.
PMID: 33489012
One of the challenges that restricts the evolving extracellular vesicle (EV) research field is the lack of a consensus method for EV separation. This may also explain the diversity of...
6.
Zieren R, Dong L, Pierorazio P, Pienta K, de Reijke T, Amend S
Med Oncol
. 2020 Mar;
37(4):28.
PMID: 32172294
Renal cell carcinoma is a lethal disease that is often discovered incidentally. New non-invasive biomarkers are needed to aid diagnosis and treatment. Extracellular vesicles (EVs), membranous vesicles secreted by all...
7.
Dong L, Zieren R, Xue W, de Reijke T, Pienta K
Asian J Urol
. 2019 Feb;
6(1):26-41.
PMID: 30775246
Metastatic prostate cancer patients present in two ways-with already disseminated disease at the time of presentation or with disease recurrence after definitive local therapy. Androgen deprivation therapy is given as...
8.
Dong L, Zieren R, Wang Y, de Reijke T, Xue W, Pienta K
Biochim Biophys Acta Rev Cancer
. 2019 Feb;
1871(2):342-360.
PMID: 30738098
Urological malignancies, including prostate cancer, bladder cancer and kidney cancer, are major causes of morbidity and mortality worldwide. Because of the high incidence, diversity in biology, and especially direct interaction...