Richard B M Schasfoort
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Explore the profile of Richard B M Schasfoort including associated specialties, affiliations and a list of published articles.
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38
Citations
988
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Recent Articles
1.
Schasfoort R
Anal Biochem
. 2023 Feb;
667:115085.
PMID: 36809845
The value of the affinity constants (kd, ka, and KD) that are determined by label free interaction analysis methods are strongly affected by the ligand density at the sensor surface...
2.
Hendriks J, Schasfoort R, Huskens J, Saris D, Karperien M
Anal Biochem
. 2022 Sep;
658:114918.
PMID: 36170905
Biomarker measurements are essential for the early diagnosis of complex diseases. However, many current biomarker assays lack sensitivity and multiplexing capacity, work in a narrow detection range and importantly lack...
3.
Schasfoort R, van Weperen J, van Amsterdam M, Parisot J, Hendriks J, Koerselman M, et al.
MethodsX
. 2021 Jul;
8:101432.
PMID: 34221910
Surface Plasmon Resonance imaging (SPRi) was used to determine the presence and strength of binding of IgG, IgM and IgA against the Receptor Binding Domain (RBD) of SARS-CoV-2 in sera...
4.
Schasfoort R, van Weperen J, van Amsterdam M, Parisot J, Hendriks J, Koerselman M, et al.
Biosens Bioelectron
. 2021 Apr;
183:113165.
PMID: 33799060
Surface Plasmon Resonance imaging (SPRi) was used to determine the presence and strength of binding of IgG, IgM and IgA against the Receptor Binding Domain (RBD) of SARS-CoV-2 in sera...
5.
Krishnamoorthy G, Carlen E, Beusink J, Schasfoort R, van den Berg A
Anal Methods
. 2020 Sep;
1(3):162-169.
PMID: 32938053
Binding affinity of biomolecular interactions can be directly extracted from measured surface plasmon resonance biosensor sensorgrams by fitting the data to the appropriate model equations. The conventional method for affinity...
6.
Shinde P, Howie H, Stegmann T, Hay A, Waterman H, Szittner Z, et al.
Front Immunol
. 2020 Aug;
11:1516.
PMID: 32765523
It has long been appreciated that immunoglobulins are not just the effector endpoint of humoral immunity, but rather have a complex role in regulating antibody responses themselves. Donor derived anti-RhD...
7.
Stojanovic I, Ruivo C, van der Velden T, Schasfoort R, Terstappen L
Biosensors (Basel)
. 2019 May;
9(2).
PMID: 31137820
Rapid multiplex cell surface marker analysis can expedite investigations in which large number of antigens need to be analyzed. Simultaneous analysis of multiple surface antigens at the same level of...
8.
Abali F, Broekmaat J, Tibbe A, Schasfoort R, Zeune L, Terstappen L
Lab Chip
. 2019 May;
19(10):1850-1859.
PMID: 31041434
Here we describe a combined method to monitor the secretion of molecules produced by single cells, followed by a method to isolate the individual cells that produced these molecules. The...
9.
Schasfoort R, Abali F, Stojanovic I, Vidarsson G, Terstappen L
Biosensors (Basel)
. 2018 Nov;
8(4).
PMID: 30380705
SPR cytometry entails the measurement of parameters from intact cells using the surface plasmon resonance (SPR) phenomenon. Specific real-time and label-free binding of living cells to sensor surfaces has been...
10.
Hendriks J, Stojanovic I, Schasfoort R, Saris D, Karperien M
Anal Chem
. 2018 May;
90(11):6563-6571.
PMID: 29732889
There is a large unmet need for reliable biomarker measurement systems for clinical application. Such systems should meet challenging requirements for large scale use, including a large dynamic detection range,...