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Richard B Gillis

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Articles 33
Citations 354
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Recent Articles
1.
Chun T, Pattem J, Gillis R, Dinu V, Yakubov G, Corfield A, et al.
Sci Rep . 2023 Jul; 13(1):11367. PMID: 37443326
Glycopeptide antibiotics are regularly used in ophthalmology to treat infections of Gram-positive bacteria. Aggregative interactions of antibiotics with mucins however can lead to long exposure and increases the risk of...
2.
Abu Hammad K, Dinu V, MacCalman T, Pattem J, Goodall M, Gillis R, et al.
Eur Biophys J . 2023 May; 52(4-5):439-443. PMID: 37195494
The solution properties of two different glycoforms of IgG1 (IgG1Cri and IgG1Wid) are compared using primarily sedimentation equilibrium analysis with two complementary analysis routines: SEDFIT-MSTAR and MULTISIG. IgGCri bears diantennary...
3.
Jacob P, Brugnoli B, Del Giudice A, Phan H, Chauhan V, Beckett L, et al.
J Colloid Interface Sci . 2023 Mar; 641:1043-1057. PMID: 36996683
Sustainably derived poly(glycerol adipate) (PGA) has been deemed to deliver all the desirable features expected in a polymeric scaffold for drug-delivery, including biodegradability, biocompatibility, self-assembly into nanoparticles (NPs) and a...
4.
Chun T, Pattem J, Gillis R, Dinu V, Yakubov G, Corfield A, et al.
Sci Rep . 2023 Feb; 13(1):1969. PMID: 36737502
The natural glycopeptide antibiotic teicoplanin is used for the treatment of serious Gram-positive related bacterial infections and can be administered intravenously, intramuscularly, topically (ocular infections), or orally. It has also...
5.
Gillis R, Solomon H, Govada L, Oldham N, Dinu V, Jiwani S, et al.
Sci Rep . 2021 Jan; 11(1):1737. PMID: 33462295
This study concerns glulisine, a rapid-acting insulin analogue that plays a fundamental role in diabetes management. We have applied a combination of methods namely X-ray crystallography, and biophysical characterisation to...
6.
Wakefield J, Hampe R, Gillis R, Sitterli A, Adams G, Kutzke H, et al.
Eur Biophys J . 2020 Aug; 49(8):791-798. PMID: 32844285
The 6-deoxy-6-aminocelluloses-or "aminocelluloses"-are a class of synthetic natural cellulose derivatives which are mostly aqueous soluble and have excellent film-forming properties. Recent studies have connected these properties at the molecular level...
7.
Jiwani S, Gillis R, Besong D, Almutairi F, Erten T, Kok M, et al.
Polymers (Basel) . 2020 Jul; 12(8). PMID: 32722155
Cucurbits are plants that have been used frequently as functional foods. This study includes the extraction, isolation, and characterisation of the mesocarp polysaccharide of . The polysaccharide component was purified...
8.
Beji O, Gillis R, Dinu V, Jiwani S, Gyasi-Antwi P, Fisk I, et al.
Eur J Pharm Biopharm . 2020 May; 152:340-347. PMID: 32446962
Purpose: Insulin, in typical use, undergoes multiple changes in temperature; from refrigerator, to room temperature, to body temperature. Although long-term storage temperature has been well-studied, the short term changes to...
9.
Jiwani S, Huang S, Beji O, Gyasi-Antwi P, Gillis R, Adams G
Polymers (Basel) . 2020 Feb; 12(2). PMID: 32050432
Protein polysaccharide complexes have been widely studied for multiple industrial applications and are popular due to their biocompatibility. Insulin degludec, an analogue of human insulin, exists as di-hexamer in pharmaceutical...
10.
Dinu V, Gillis R, MacCalman T, Lim M, Adams G, Harding S, et al.
Food Biophys . 2019 Aug; 14(3):278-286. PMID: 31402849
Submaxillary mucin is a major component that defines the makeup and functionality of saliva. Understanding its structure and function during food intake is key to designing appropriate strategies for enhancing...