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Richard A Amos

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Articles 31
Citations 313
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Recent Articles
1.
Green S, Lourenco A, Palmans H, Lee N, Amos R, Souza D, et al.
Phys Med Biol . 2025 Jan; 70(6). PMID: 39842088
Internationally, reference dosimetry for clinical proton beams largely follows the guidelines published by the International Atomic Energy Agency (IAEA TRS-398 Rev. 1 (2024). This approach yields a relative standard uncertainty...
2.
Chhabra A, Amos R, Simone 2nd C, Simone C, Kaiser A, Perles L, et al.
Int J Radiat Oncol Biol Phys . 2025 Jan; PMID: 39761799
Radiation therapy manages pancreatic cancer in various settings; however, the proximity of gastrointestinal (GI) luminal organs at risk (OARs) poses challenges to conventional radiation therapy. Proton beam therapy (PBT) may...
3.
Fenwick J, Mayhew C, Jolly S, Amos R, Hawkins M
Front Oncol . 2024 Jul; 14:1420337. PMID: 39022584
Ultra-high dose-rate 'FLASH' radiotherapy may be a pivotal step forward for cancer treatment, widening the therapeutic window between radiation tumour killing and damage to neighbouring normal tissues. The extent of...
4.
Kumar S, Larson R, Stecklein S, Reddy J, Debeb B, Amos R, et al.
bioRxiv . 2024 Jun; PMID: 38854130
Purpose: Inhibiting HMG-CoA reductase with simvastatin prevents breast cancer metastases in preclinical models and radiosensitizes monolayer and stem-like IBC cell lines . Given the extensive use of simvastatin worldwide and...
5.
Solovyov A, Verkhovtsev A, Mason N, Amos R, Bald I, Baldacchino G, et al.
Chem Rev . 2024 Jun; 124(13):8014-8129. PMID: 38842266
This roadmap reviews the new, highly interdisciplinary research field studying the behavior of condensed matter systems exposed to radiation. The Review highlights several recent advances in the field and provides...
6.
Choi J, Wojcieszynski A, Amos R, Giap H, Apisarnthanarax S, Ashman J, et al.
Int J Part Ther . 2024 May; 11:100019. PMID: 38757077
Purpose: Radiotherapy delivery in the definitive management of lower gastrointestinal (LGI) tract malignancies is associated with substantial risk of acute and late gastrointestinal (GI), genitourinary, dermatologic, and hematologic toxicities. Advanced...
7.
Caruana C, Amos R, Burgos D, Heukelom S, Jeremic M, Julkunen P, et al.
Phys Med . 2023 May; 111:102602. PMID: 37244072
Although Medical Physics educators have historically contributed to the education of the non-physics healthcare professions, their role was not studied in a systematic manner. In 2009, EFOMP set up a...
8.
Lourenco A, Subiel A, Lee N, Flynn S, Cotterill J, Shipley D, et al.
Sci Rep . 2023 Feb; 13(1):2054. PMID: 36739297
A paradigm shift is occurring in clinical oncology exploiting the recent discovery that short pulses of ultra-high dose rate (UHDR) radiation-FLASH radiotherapy-can significantly spare healthy tissues whilst still being at...
9.
Zhang Y, Alshaikhi J, Amos R, Tan W, Anaya V, Pang Y, et al.
Med Phys . 2022 Sep; 49(12):7683-7693. PMID: 36083223
Purpose: To incorporate small non-rigid variations of head and neck patients into the robust evaluation of intensity-modulated proton therapy (IMPT) for the selection of robust treatment plans. Methods: A cohort...
10.
Lee E, Lourenco A, Speth J, Lee N, Subiel A, Romano F, et al.
Med Phys . 2022 Jul; 49(9):6171-6182. PMID: 35780318
Purpose: To provide ultrahigh dose rate (UHDR) pencil beam scanning (PBS) proton dosimetry comparison of clinically used plane-parallel ion chambers, PTW (Physikalisch-Technische Werkstaetten) Advanced Markus and IBA (Ion Beam Application)...