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Riccardo Zenezini Chiozzi

Explore the profile of Riccardo Zenezini Chiozzi including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 635
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Recent Articles
1.
Newton L, Gathmann C, Ridewood S, Smith R, Wijaya A, Hornsby T, et al.
Nat Commun . 2025 Feb; 16(1):1484. PMID: 39929804
Targeting host proteins that are crucial for viral replication offers a promising antiviral strategy. We have designed and characterised antiviral PROteolysis TArgeting Chimeras (PROTACs) targeting the human protein cyclophilin A...
2.
Ji R, Chiozzi R, van den Toorn H, Leung M, Zeev-Ben-Mordehai T, Burke N, et al.
Mol Cell Proteomics . 2024 Dec; 24(1):100893. PMID: 39674511
Sperm cells are terminally differentiated cells that are essential for reproduction in sexually reproducing species. Consistent with their highly specialized function, sperm cells harbor a unique proteome containing many proteins...
3.
Erinjeri A, Wang X, Williams R, Chiozzi R, Thalassinos K, Labbadia J
Nat Commun . 2024 Nov; 15(1):9797. PMID: 39532882
Increased activity of the heat shock factor, HSF-1, suppresses proteotoxicity and enhances longevity. However, the precise mechanisms by which HSF-1 promotes lifespan are unclear. Using an RNAi screen, we identify...
4.
Reinisch I, Michenthaler H, Sulaj A, Moyschewitz E, Krstic J, Galhuber M, et al.
Nat Commun . 2024 Feb; 15(1):1391. PMID: 38360943
In obesity, sustained adipose tissue (AT) inflammation constitutes a cellular memory that limits the effectiveness of weight loss interventions. Yet, the impact of fasting regimens on the regulation of AT...
5.
Lozano-Terol G, Chiozzi R, Gallego-Jara J, Sola-Martinez R, Vivancos A, Ortega A, et al.
iScience . 2024 Feb; 27(2):109017. PMID: 38333705
Nε-lysine acetylation is a common posttranslational modification observed in . In the present study, integrative analysis of the proteome and acetylome was performed using label-free quantitative mass spectrometry to analyze...
6.
Leung M, Zeng J, Wang X, Roelofs M, Huang W, Chiozzi R, et al.
Cell . 2023 Jun; 186(13):2880-2896.e17. PMID: 37327785
Sperm motility is crucial to reproductive success in sexually reproducing organisms. Impaired sperm movement causes male infertility, which is increasing globally. Sperm are powered by a microtubule-based molecular machine-the axoneme-but...
7.
Levray Y, Bana B, Tarr S, McLaughlin E, Rossi-Smith P, Waltho A, et al.
PLoS Pathog . 2023 Mar; 19(3):e1011281. PMID: 37000891
During the blood stage of a malaria infection, malaria parasites export both soluble and membrane proteins into the erythrocytes in which they reside. Exported proteins are trafficked via the parasite...
8.
Zhang M, Chiozzi R, Bromfield E, Heck A, Helms J, Gadella B
Andrology . 2023 Feb; 11(7):1460-1471. PMID: 36815564
Background: Previously, we reported that cysteine-rich secretory protein 2 is involved in high molecular weight complexes in boar spermatozoa. These cysteine-rich secretory protein 2protein complexes are formed at the last...
9.
Magrinelli F, Rocca C, Simone R, Chiozzi R, Jaunmuktane Z, Mencacci N, et al.
Mov Disord . 2022 Nov; 38(2):347-353. PMID: 36420574
Background: Heterozygous NKX2-1 loss-of-function variants cause combinations of hyperkinetic movement disorders (MDs, particularly childhood-onset chorea), pulmonary dysfunction, and hypothyroidism. Mobile element insertions (MEIs) are potential disease-causing structural variants whose detection...
10.
Digiacomo L, Giulimondi F, Capriotti A, Piovesana S, Montone C, Chiozzi R, et al.
Nanoscale Adv . 2022 Sep; 3(13):3824-3834. PMID: 36133013
In the past few years, characterization of the protein corona (PC) that forms around liposomal systems has gained increasing interest for the development of novel therapeutic and diagnostic technologies. At...