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Rhona J McVey

Explore the profile of Rhona J McVey including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 270
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Recent Articles
1.
Barr C, Sergeant J, Agnew H, Bolton J, McVey R, Crosbie E
BJOG . 2023 Jan; 130(8):941-948. PMID: 36715558
Objective: To investigate serum human epididymis-4 (HE4) as a predictive biomarker of intrauterine progestin response in endometrial cancer and atypical endometrial hyperplasia (AEH). Design: Prospective prognostic factor study. Setting: Consecutive...
2.
Naqvi A, MacKintosh M, Derbyshire A, Tsakiroglou A, Walker T, McVey R, et al.
Int J Obes (Lond) . 2021 Dec; 46(3):605-612. PMID: 34857870
Background: The incidence of endometrial cancer is rising in parallel with the obesity epidemic. Obesity increases endometrial cancer risk and weight loss is protective, but the underlying mechanisms are incompletely...
3.
Barr C, Ryan N, Derbyshire A, Wan Y, MacKintosh M, McVey R, et al.
Cancer Prev Res (Phila) . 2021 Aug; 14(11):1041-1050. PMID: 34348914
Intrauterine progestin is a treatment option for women with atypical hyperplasia or low-risk endometrial cancer who wish to preserve their fertility, or whose poor surgical fitness precludes safe hysterectomy. We...
4.
Evans D, Lalloo F, Ryan N, Bowers N, Green K, Woodward E, et al.
J Med Genet . 2021 Jan; 59(4):328-334. PMID: 33452216
Background: Testing cancers for mismatch repair deficiency (dMMR) by immunohistochemistry (IHC) is a quick and inexpensive means of triaging individuals for germline Lynch syndrome testing. The aim of this study...
5.
Ryan N, McMahon R, Tobi S, Snowsill T, Esquibel S, Wallace A, et al.
PLoS Med . 2020 Sep; 17(9):e1003263. PMID: 32941469
Background: Lynch syndrome (LS) predisposes to endometrial cancer (EC), colorectal cancer, and other cancers through inherited pathogenic variants affecting mismatch-repair (MMR) genes. Diagnosing LS in women with EC can reduce...
6.
Crosbie E, Ryan N, McVey R, Lalloo F, Bowers N, Green K, et al.
J Med Genet . 2020 Sep; 58(10):687-691. PMID: 32917768
Background: Hereditary causes of ovarian cancer include Lynch syndrome, which is due to inherited pathogenic variants affecting one of the four mismatch repair genes involved in DNA repair. The aim...
7.
Paraskevaidi M, Morais C, Ashton K, Stringfellow H, McVey R, Ryan N, et al.
Cancers (Basel) . 2020 May; 12(5). PMID: 32429365
Endometrial cancer is the sixth most common cancer in women, with a rising incidence worldwide. Current approaches for the diagnosis and screening of endometrial cancer are invasive, expensive or of...
8.
Behrouzi R, Ryan N, Barr C, Derbyshire A, Wan Y, Maskell Z, et al.
Cancers (Basel) . 2020 Jan; 12(2). PMID: 31979212
The levonorgestrel-releasing intrauterine system (LNG-IUS) is a conservative management option for atypical hyperplasia (AH) and low grade early stage endometrial cancer (EEC), but around 1 in 3 patients fail to...
9.
MacKintosh M, Derbyshire A, McVey R, Bolton J, Nickkho-Amiry M, Higgins C, et al.
Int J Cancer . 2018 Oct; 144(3):641-650. PMID: 30289975
Obesity is the strongest risk factor for endometrial cancer (EC). To inform targeted screening and prevention strategies, we assessed the impact of obesity and subsequent bariatric surgery-induced weight loss on...
10.
Latif A, Chadwick A, Kitson S, Gregson H, Sivalingam V, Bolton J, et al.
BMC Clin Pathol . 2018 Jan; 17:27. PMID: 29299023
Background: Endometrial cancer (EC) is a major health concern due to its rising incidence. Whilst early stage disease is generally cured by surgery, advanced EC has a poor prognosis with...