Reyhaneh Lahmy
Overview
Explore the profile of Reyhaneh Lahmy including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
174
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Recent Articles
1.
Tran D, Pottekat A, Mir S, Loguercio S, Jang I, Campos A, et al.
Diabetes
. 2020 May;
69(8):1723-1734.
PMID: 32457219
The β-cell protein synthetic machinery is dedicated to the production of mature insulin, which requires the proper folding and trafficking of its precursor, proinsulin. The complete network of proteins that...
2.
Scully K, Lahmy R, Signaevskaia L, Sasik R, Medal R, Kim H, et al.
Cell Mol Gastroenterol Hepatol
. 2018 Jul;
6(2):181-198.
PMID: 30003124
Background & Aims: Oncogenic mutations in KRAS, coupled with inactivation of p53, CDKN2A/p16, and SMAD4, drive progression of pancreatic ductal adenocarcinoma (PDA). Overexpression of MYC and deregulation of retinoblastoma (RB)...
3.
Villarino N, Signaevskaia L, van Niekerk J, Medal R, Kim H, Lahmy R, et al.
Oncotarget
. 2017 Sep;
8(32):53154-53167.
PMID: 28881801
The average survival for patients with Pancreatic Ductal Adenocarcinoma (PDA) is merely 6 months, underscoring the need for new therapeutic approaches. During PDA progression, pancreatic acinar cells lose activity of...
4.
Kim S, Lahmy R, Riha C, Yang C, Jakubison B, van Niekerk J, et al.
Pancreas
. 2015 Apr;
44(5):718-27.
PMID: 25894862
Objectives: Pancreatic ductal adenocarcinoma (PDA) initiates from quiescent acinar cells that attain a Kras mutation, lose signaling from basic helix-loop-helix (bHLH) transcription factors, undergo acinar-ductal metaplasia, and rapidly acquire increased...
5.
Lahmy R, Bolyukh V, Castilla S, Laurent L, Katkov I, Itkin-Ansari P
Cryobiology
. 2015 Mar;
70(3):283-6.
PMID: 25817378
We have previously shown that human embryonic stem cell derived islet progenitors (hESC-IPs), encapsulated inside an immunoprotective device, mature in vivo and ameliorate diabetes in mice. The ability to cryopreserve...
6.
Mobarra N, Soleimani M, Kouhkan F, Hesari Z, Lahmy R, Mossahebi-Mohammadi M, et al.
Int J Hematol Oncol Stem Cell Res
. 2015 Mar;
8(4):20-9.
PMID: 25774264
Background: The use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. Differentiation of human induced Pluripotent Stem Cells (hiPSCs) to Hepatocyte-like Cells (HLCs)...
7.
Kirk K, Hao E, Lahmy R, Itkin-Ansari P
Stem Cell Res
. 2014 May;
12(3):807-14.
PMID: 24788136
There are several challenges to successful implementation of a cell therapy for insulin dependent diabetes derived from human embryonic stem cells (hESC). Among these are development of functional insulin producing...
8.
Lahmy R, Soleimani M, Sanati M, Behmanesh M, Kouhkan F, Mobarra N
Mol Biol Rep
. 2014 Jan;
41(4):2055-66.
PMID: 24469711
Islet transplantation is considered as an ultimate option for the treatment of type I diabetes. Human induced pluripotent stem cells (hiPSCs) have raised the possibility that patient-specific insulin-secreting cells might...
9.
Kouhkan F, Hafizi M, Mobarra N, Mossahebi-Mohammadi M, Mohammadi S, Behmanesh M, et al.
Appl Biochem Biotechnol
. 2013 Dec;
172(4):2055-69.
PMID: 24326679
Micro RNAs (miRNAs) are a novel class of non-coding regulatory RNA molecules that contribute to post-transcriptional gene regulation. Recent studies have demonstrated that specific miRNAs such as miR-150, miR-154, and...
10.
Kouhkan F, Soleimani M, Daliri M, Behmanesh M, Mobarra N, Mossahebi Mohammadi M, et al.
Iran J Basic Med Sci
. 2013 Sep;
16(6):756-63.
PMID: 23997901
Objective(s): Erythropoiesis is regulated by some extrinsic and intrinsic factors as microRNAs (miRNAs). miRNAs are endogenously small non-coding regulatory RNAs which play vital roles in the variety of cellular fate,...