Rex Gonzales
Overview
Explore the profile of Rex Gonzales including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
11
Followers
0
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Recent Articles
1.
Wang L, Tsakiroglou P, Gonzales R, Cho S, Li A, Dos Remedios C, et al.
JCI Insight
. 2023 Dec;
9(3).
PMID: 38127465
Obscurins are giant cytoskeletal proteins with structural and regulatory roles. Obscurin-B (~870 kDa), the largest known isoform, contains 2 enzymatically active Ser/Thr kinase (kin) domains, kin1 and kin2, which belong...
2.
Hwang B, Gonzales R, Corzine S, Stenson E, Pidugu L, Lu A
PLoS One
. 2022 Aug;
17(8):e0272645.
PMID: 35939452
The Rad9-Rad1-Hus1 checkpoint clamp activates the DNA damage response and promotes DNA repair. DNA loading on the central channel of the Rad9-Rad1-Hus1 complex is required to execute its biological functions....
3.
Gupta A, Hwang B, Benyamien-Roufaeil D, Jain S, Liu S, Gonzales R, et al.
OBM Geriat
. 2022 Jul;
6(2).
PMID: 35812693
Telomeres consist of special features and proteins to protect the ends of each chromosome from deterioration and fusion. The telomeric DNA repeats are highly susceptible to oxidative damage that can...
4.
Tan J, Wang X, Hwang B, Gonzales R, Konen O, Lan L, et al.
Aging (Albany NY)
. 2020 Sep;
12(18):17761-17785.
PMID: 32991318
In the base excision repair pathway, MYH/MUTYH DNA glycosylase prevents mutations by removing adenine mispaired with 8-oxoG, a frequent oxidative lesion. MYH glycosylase activity is enhanced by Rad9-Rad1-Hus1 (9-1-1) checkpoint...