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Renee R Ram

Explore the profile of Renee R Ram including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 256
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Recent Articles
1.
Link J, Rhee M, Tse W, Zheng J, Somoza J, Rowe W, et al.
Nature . 2020 Jul; 584(7822):614-618. PMID: 32612233
Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV, and can prevent new infections via pre-exposure prophylaxis. However, some people living with HIV who are heavily...
2.
Ram R, Duatschek P, Margot N, Abram M, Geleziunas R, Hesselgesser J, et al.
Antivir Ther . 2020 May; 25(3):163-169. PMID: 32420906
Background: Vesatolimod (VES; GS-9620) is a Toll-like receptor 7 (TLR7) agonist that directly activates human plasmacytoid dendritic cells (pDCs) and B lymphocytes resulting in direct and indirect production of cytokines...
3.
Yant S, Mulato A, Hansen D, Tse W, Niedziela-Majka A, Zhang J, et al.
Nat Med . 2019 Sep; 25(9):1377-1384. PMID: 31501601
People living with HIV (PLWH) have expressed concern about the life-long burden and stigma associated with taking pills daily and can experience medication fatigue that might lead to suboptimal treatment...
4.
Margot N, Ram R, White K, Abram M, Callebaut C
J Med Virol . 2019 Aug; 91(12):2188-2194. PMID: 31389026
The development of resistance to human immunodeficiency virus 1 (HIV-1) integrase strand-transfer inhibitors (INSTI) has been documented; however, knowledge of the impact of pre-existing integrase (IN) mutations on INSTI resistance...
5.
Abram M, Ram R, Margot N, Barnes T, White K, Callebaut C, et al.
PLoS One . 2017 Feb; 12(2):e0172206. PMID: 28212411
T97A is an HIV-1 integrase polymorphism associated with integrase strand transfer inhibitor (INSTI) resistance. Using pooled data from 16 clinical studies, we investigated the prevalence of T97A (pre-existing and emergent)...