Rene Maehr
Overview
Explore the profile of Rene Maehr including associated specialties, affiliations and a list of published articles.
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Articles
56
Citations
5134
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Recent Articles
1.
Pardo-Palacios F, Wang D, Reese F, Diekhans M, Carbonell-Sala S, Williams B, et al.
Nat Methods
. 2024 Jun;
21(7):1349-1363.
PMID: 38849569
The Long-read RNA-Seq Genome Annotation Assessment Project Consortium was formed to evaluate the effectiveness of long-read approaches for transcriptome analysis. Using different protocols and sequencing platforms, the consortium generated over...
2.
Chen Y, Lei X, Jiang Z, Humphries F, Parsi K, Mustone N, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(47):e2308355120.
PMID: 37963251
A detailed understanding of the innate immune mechanisms involved in restricting SARS-CoV-2 infection and how the virus disrupts these processes could reveal new strategies to boost antiviral mechanisms and develop...
3.
Kearns N, Lobo M, Genga R, Abramowitz R, Parsi K, Min J, et al.
Dev Cell
. 2023 Sep;
58(18):1801-1818.e15.
PMID: 37751684
Approaches to study human pharyngeal foregut endoderm-a developmental intermediate that is linked to various human syndromes involving pharynx development and organogenesis of tissues such as thymus, parathyroid, and thyroid-have been...
4.
Frantz W, Iyengar S, Neiswender J, Cousineau A, Maehr R, Ceol C
Elife
. 2023 Apr;
12.
PMID: 37021774
Tissue-resident stem and progenitor cells are present in many adult organs, where they are important for organ homeostasis and repair in response to injury. However, the signals that activate these...
5.
Hariharan V, Shin M, Chang C, OReilly D, Biscans A, Yamada K, et al.
Proc Natl Acad Sci U S A
. 2023 Mar;
120(11):e2219523120.
PMID: 36893269
The continuous evolution of SARS-CoV-2 variants complicates efforts to combat the ongoing pandemic, underscoring the need for a dynamic platform for the rapid development of pan-viral variant therapeutics. Oligonucleotide therapeutics...
6.
Landshammer A, Bolondi A, Kretzmer H, Much C, Buschow R, Rose A, et al.
Elife
. 2023 Jan;
12.
PMID: 36719724
Long non-coding RNAs (lncRNAs) have emerged as fundamental regulators in various biological processes, including embryonic development and cellular differentiation. Despite much progress over the past decade, the genome-wide annotation of...
7.
Shin M, Chan I, Cao Y, Gruntman A, Lee J, Sousa J, et al.
Nucleic Acids Res
. 2022 Aug;
50(15):8418-8430.
PMID: 35920332
The lung is a complex organ with various cell types having distinct roles. Antisense oligonucleotides (ASOs) have been studied in the lung, but it has been challenging to determine their...
8.
Guo D, Daman K, Chen J, Shi M, Yan J, Matijasevic Z, et al.
Elife
. 2022 Jan;
11.
PMID: 35076017
Skeletal muscle myoblasts (iMyoblasts) were generated from human induced pluripotent stem cells (iPSCs) using an efficient and reliable transgene-free induction and stem cell selection protocol. Immunofluorescence, flow cytometry, qPCR, digital...
9.
Magaletta M, Lobo M, Kernfeld E, Aliee H, Huey J, Parsons T, et al.
Nat Commun
. 2022 Jan;
13(1):457.
PMID: 35075189
Maldevelopment of the pharyngeal endoderm, an embryonic tissue critical for patterning of the pharyngeal region and ensuing organogenesis, ultimately contributes to several classes of human developmental syndromes and disorders. Such...
10.
Oksuz B, Yang L, Abraham S, Venev S, Krietenstein N, Parsi K, et al.
Nat Methods
. 2021 Sep;
18(9):1046-1055.
PMID: 34480151
Chromosome conformation capture (3C) assays are used to map chromatin interactions genome-wide. Chromatin interaction maps provide insights into the spatial organization of chromosomes and the mechanisms by which they fold....