Rene M Roy
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Explore the profile of Rene M Roy including associated specialties, affiliations and a list of published articles.
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9
Citations
464
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Recent Articles
1.
Roy R, Allawzi A, Burns N, Sul C, Rubio V, Graham J, et al.
FASEB J
. 2023 Nov;
37(12):e23316.
PMID: 37983890
Alveolar inflammation is a hallmark of acute lung injury (ALI), and its clinical correlate is acute respiratory distress syndrome-and it is as a result of interactions between alveolar type II...
2.
Roy R, Klein B
Curr Opin Microbiol
. 2013 Apr;
16(4):404-8.
PMID: 23602359
Human exposure to fungi results in a wide range of health outcomes, from invasive disease or allergy to immune tolerance. Inhaled fungi contact airway epithelial cells as an early event,...
3.
Roy R, Paes H, Nanjappa S, Sorkness R, Gasper D, Sterkel A, et al.
mBio
. 2013 Apr;
4(2).
PMID: 23549917
Levels of the anaphylatoxin C3a are increased in patients with asthma compared with those in nonasthmatics and increase further still during asthma exacerbations. However, the role of C3a during sensitization...
4.
Roy R, Wuthrich M, Klein B
J Immunol
. 2012 Aug;
189(5):2545-52.
PMID: 22851704
Chitin exposure in the lung induces eosinophilia and alternative activation of macrophages and is correlated with allergic airway disease. However, the mechanism underlying chitin-induced polarization of macrophages is poorly understood....
5.
Roy R, Klein B
Cell Host Microbe
. 2012 May;
11(5):436-46.
PMID: 22607797
Life-threatening fungal infections have increased in recent years while treatment options remain limited. The development of vaccines against fungal pathogens represents a key advance sorely needed to combat the increasing...
6.
Feire A, Roy R, Manley K, Compton T
J Virol
. 2010 Jul;
84(19):10026-37.
PMID: 20660204
Cellular integrins were identified as human cytomegalovirus (HCMV) entry receptors and signaling mediators in both fibroblasts and endothelial cells. The goal of these studies was to determine the mechanism by...
7.
Levy O, Coughlin M, Cronstein B, Roy R, Desai A, Wessels M
J Immunol
. 2006 Jul;
177(3):1956-66.
PMID: 16849509
Human newborns are susceptible to microbial infection and mount poor vaccine responses, yet the mechanisms underlying their susceptibility are incompletely defined. We have previously reported that despite normal basal expression...
8.
Levy O, Zarember K, Roy R, Cywes C, Godowski P, Wessels M
J Immunol
. 2004 Sep;
173(7):4627-34.
PMID: 15383597
Newborns are at increased risk of overwhelming infection, yet the mechanisms underlying this susceptibility are incompletely defined. In this study we report a striking 1- to 3-log decrease in sensitivity...
9.
Orange J, Levy O, Brodeur S, Krzewski K, Roy R, Niemela J, et al.
J Allergy Clin Immunol
. 2004 Sep;
114(3):650-6.
PMID: 15356572
Background: Many receptors rely on the appropriate activation of nuclear factor (NF) kappa B to induce cellular function. This process depends critically on the phosphorylation of the inhibitor of NF-kappa...