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Renato Scacchi

Explore the profile of Renato Scacchi including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 243
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Recent Articles
1.
Scarabino D, Scacchi R, Pinto A, Corbo R
Rejuvenation Res . 2015 May; 18(5):464-72. PMID: 25936248
Evolutionary theories of aging predict an antagonistic relationship between fertility and life span in humans, but the genetic basis of this phenomenon is not clear. The variation of three genes...
2.
Corbo R, Gambina G, Broggio E, Scarabino D, Scacchi R
J Neurol Sci . 2014 Jul; 344(1-2):149-53. PMID: 25012481
The greater predisposition of women to Alzheimer's disease (AD), owing to the decrease in postmenopausal estrogen, may be influenced by polymorphic variation in genes regulating estrogen metabolism (e.g., COMT) and...
3.
Scacchi R, Gambina G, Broggio E, Corbo R
Int J Geriatr Psychiatry . 2013 Oct; 29(6):610-5. PMID: 24150894
Background: Many factors could be responsible for the different response to treatment with the cholinesterase inhibitors (ChEIs) donepezil and rivastigmine in Alzheimer's disease (AD) patients. Sex and the variants of...
4.
Corbo R, Pinto A, Scacchi R
Rejuvenation Res . 2012 Sep; 16(1):21-7. PMID: 22985084
Men and women have different life expectancies. Not unexpectedly, several genes involved in life span determination have been found to influence the probability of achieving longevity differently in men and...
5.
Corbo R, Gambina G, Scacchi R
PLoS One . 2012 Apr; 7(4):e35431. PMID: 22532853
Studies on human fertility genes have identified numerous risk/protective alleles involved in the occurrence of reproductive system diseases causing infertility or subfertility. Investigations we carried out in populations at natural...
6.
Corbo R, Gambina G, Broggio E, Scacchi R
Dement Geriatr Cogn Disord . 2011 Aug; 32(1):63-9. PMID: 21865747
Background: The higher prevalence of sporadic Alzheimer's disease (AD) in women may be explained by their longer life expectancy, but also by biological gender-specific factors such as a woman's past...
7.
Scacchi R, Ruggeri M, Corbo R
Clin Chim Acta . 2011 Apr; 412(15-16):1341-4. PMID: 21473860
Butyrylcholinesterase (BChE) and acetylcholinesterase (AchE) are two enzymes of the cholinergic system putatively involved in coronary artery disease (CAD). We investigated two single nucleotide polymorphisms (SNPs) of the genes encoding...
8.
Corbo R, Ulizzi L, Positano L, Scacchi R
J Gerontol A Biol Sci Med Sci . 2010 Sep; 66(1):51-5. PMID: 20819792
Aromatase (CYP19) and estrogen receptor-alpha (ESR1) are involved in the metabolism of estrogens, which have a relevant role in female and male aging. Moreover, due to their influence on fertility,...
9.
Scacchi R, Gambina G, Moretto G, Corbo R
J Neural Transm (Vienna) . 2009 Aug; 116(9):1179-84. PMID: 19657586
An important pathological aspect of Alzheimer's disease (AD) is the apoptosis of neuronal and glial cells. Two members of the same protein family that regulates many genes involved in apoptosis...
10.
Corbo R, Gambina G, Ulizzi L, Moretto G, Scacchi R
Dement Geriatr Cogn Disord . 2009 May; 27(6):513-8. PMID: 19478482
Background/aims: There is evidence for a higher prevalence of Alzheimer's disease (AD) in women, but whether this is due to their longer life expectancy or to biological gender-specific risk factors...