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Renan C Castillo

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Articles 118
Citations 1892
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Recent Articles
1.
Obremskey W, OToole R, Morshed S, Tornetta 3rd P, Murray C, Jones C, et al.
JAMA Surg . 2025 Jan; 160(3):276-284. PMID: 39841468
Importance: Fracture-related infection (FRI) is a serious complication following fracture fixation surgery. Current treatment of FRIs entails debridement and 6 weeks of intravenous (IV) antibiotics. Lab data and retrospective clinical...
2.
Overmann A, Carlini A, OToole R, Castillo R, OHara N
OTA Int . 2024 Nov; 7(4):e348. PMID: 39600729
Objectives: To develop and validate a prediction model for a deep surgical site infection (SSI) after fixation of a tibial plateau or pilon fracture. Design: Pooled data from 2 randomized...
3.
Zhao S, Yu Y, Frey K, Wegener S, Castillo R
Burns . 2024 Nov; 50(9):107292. PMID: 39520870
Background: Burns carries a high risk of severe physical damage, prolonged recovery, and mental health implications for both patients and their caregivers. While distress among caregivers of burn patients has...
4.
Saiz A, Carlini A, Castillo R, Joshi M, Huang Y, Murray C, et al.
Injury . 2024 Oct; 55(12):111953. PMID: 39442485
Objective: To determine if the results of the OXYGEN trial changed using an "as-treated" approach instead of the original "intention-to-treat" approach. The multi-center randomized controlled OXYGEN trial aimed to determine...
5.
Campbell T, Kirwan M, Behzadpour V, Langvardt T, Dallman J, Huang Y, et al.
Orthopedics . 2024 Aug; 47(5):e268-e272. PMID: 39163603
Background: The purpose of this study was to externally validate a predictive score for fracture-related infections, establishing generalizability for absolute and relative risk of infection in the setting of orthopedic...
6.
Carlini A, Agel J, Bosse M, Frey K, Staguhn E, Vallier H, et al.
J Bone Joint Surg Am . 2024 Jul; 106(19):1767-1775. PMID: 38954643
Background: The Short Musculoskeletal Function Assessment (SMFA) is a well validated, widely used patient-reported outcome (PRO) measure for orthopaedic patients. Despite its widespread use and acceptance, this measure does not...
7.
Firoozabadi R, Taylor T, Fernando N, Hsu J, Stinner D, Obremskey W, et al.
Eur J Orthop Surg Traumatol . 2024 Mar; 34(4):1845-1850. PMID: 38431894
Objectives: Malnutrition has been shown to increase complications and leads to poor outcomes in surgical patients, but it has not been studied extensively in orthopedic trauma. This study's purpose is...
8.
Allen L, OToole R, Bosse M, Obremskey W, Archer K, Cannada L, et al.
Trials . 2024 Feb; 25(1):107. PMID: 38317256
Background: Multicenter trials in orthopedic trauma are costly, yet crucial to advance the science behind clinical care. The number of sites is a key cost determinant. Each site has a...
9.
Joshi M, OToole R, Carlini A, Gary J, Obremskey W, Murray C, et al.
J Orthop Trauma . 2024 Jan; 38(4):183-189. PMID: 38206761
Objective: To determine whether intrawound vancomycin changes the bacteriology of surgical site infection pathogens and investigate the emergence of antibiotic-resistant pathogens. Methods: Design: Secondary analysis of phase III, prospective, randomized...
10.
Gitajn I, Werth P, Carlini A, Bosse M, Gary J, Firoozabadi R, et al.
JB JS Open Access . 2024 Jan; 9(1). PMID: 38196850
Background: Fracture-related infection is one of the most challenging complications in orthopaedic trauma surgery. However, the effect of infection on functional and pain-related outcomes has not been well established. The...