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Remy Robert

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Articles 26
Citations 1313
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Recent Articles
1.
Wang B, Robert R, Marques F, Rajapakse N, Kiriazis H, Mackay C, et al.
Sci Rep . 2024 Nov; 14(1):26985. PMID: 39505939
Cardiorenal fibrosis is a common feature of chronic cardiovascular disease and recent data suggests that cytokines and chemokines may also drive fibrosis. Here we tested the hypothesis that CXCR7, a...
2.
Ni D, Tan J, Robert R, Taitz J, Ge A, Potier-Villette C, et al.
Eur J Immunol . 2023 Aug; 53(11):e2350521. PMID: 37595951
Regulatory T cells (Treg) maintain immune homeostasis due to their anti-inflammatory functions. They can be generated either centrally in the thymus or in peripheral organs. Metabolites such as short-chain fatty...
3.
Fahimi F, Alam M, Ang C, Adhyatma G, Xie L, Mackay C, et al.
J Leukoc Biol . 2023 Jul; 114(4):373-380. PMID: 37478375
Targeting CXCR1 and CXCR2 chemokine receptors to block neutrophil migration to sites of inflammation is a promising therapeutic approach for various inflammatory and autoimmune diseases. However, assessing the translational potential...
4.
Alam M, Xie L, Yap Y, Robert R
Curr Protoc . 2023 Mar; 3(3):e695. PMID: 36913546
Atopic dermatitis (AD) is a chronic, relapsing, and extremely pruritic inflammatory skin disease with a particular impact on children. AD pathogenesis is not yet fully understood, and there is no...
5.
Hashad R, Jap E, Casey J, Ho Y, Wright A, Thalmann C, et al.
Chemistry . 2022 Dec; 29(11):e202202491. PMID: 36451579
A highly effective 2-step system for site-specific antibody modification and conjugation of the monoclonal antibody Herceptin (commercially available under Trastuzumab) in a cysteine-independent manner was used to generate labelled antibodies...
6.
Alam M, Xie L, Yap Y, Marques F, Robert R
Pathogens . 2022 Jun; 11(6). PMID: 35745496
Atopic dermatitis (AD) is a globally prevalent skin inflammation with a particular impact on children. Current therapies for AD are challenged by the limited armamentarium and the high heterogeneity of...
7.
Xie L, McKenzie C, Qu X, Mu Y, Wang Q, Bing N, et al.
J Immunol . 2021 Jun; 207(1):101-109. PMID: 34135065
pH sensing by GPR65 regulates various inflammatory conditions, but its role in skin remains unknown. In this study, we performed a phenome-wide association study and report that the T allele...
8.
Shen S, Kumar K, Wen S, Shim R, Wanrooy B, Stanley D, et al.
Front Immunol . 2021 Mar; 12:619366. PMID: 33708211
Ulcerative colitis is an inflammatory disease of the colon that is associated with colonic neutrophil accumulation. Recent evidence indicates that diet alters the composition of the gut microbiota and influences...
9.
Alam M, Xie L, Ang C, Fahimi F, Willingham S, Kueh A, et al.
MAbs . 2020 Dec; 12(1):1856460. PMID: 33347356
Neutrophils are the most abundant effector cells of the innate immune system and represent the first line of defense against infection. However, in many common pathologies, including autoimmune diseases, excessive...
10.
Chow S, Deo P, Yeung A, Kostoulias X, Jeon Y, Gao M, et al.
J Leukoc Biol . 2020 Jun; 108(3):967-981. PMID: 32531864
Staphylococcus aureus causes necrotizing pneumonia by secreting toxins such as leukocidins that target front-line immune cells. The mechanism by which leukocidins kill innate immune cells and trigger inflammation during S....