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Reka Kugyelka

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Articles 7
Citations 113
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Recent Articles
1.
Lacorcia M, Kugyelka R, Spechtenhauser L, Prodjinotho U, Hamway Y, Spangenberg T, et al.
Front Immunol . 2022 Jul; 13:878029. PMID: 35833137
Alongside the wide distribution throughout sub Saharan Africa of schistosomiasis, the morbidity associated with this chronic parasitic disease in endemic regions is often coupled with infection-driven immunomodulatory processes which modify...
2.
Khanfar E, Olasz K, Gabris F, Gajdocsi E, Botz B, Kiss T, et al.
Int J Mol Sci . 2020 Aug; 21(17). PMID: 32859051
B cells play a crucial role in the pathogenesis of rheumatoid arthritis. In Nkx2-3-deficient mice (Nkx2-3) the spleen's histological structure is fundamentally changed; therefore, B cell homeostasis is seriously disturbed....
3.
Prenek L, Litvai T, Balazs N, Kugyelka R, Boldizsar F, Najbauer J, et al.
Apoptosis . 2020 Aug; 25(9-10):715-729. PMID: 32737651
Earlier we have reported that thymic regulatory T cells (Treg) are resistant to in vivo glucocorticoid hormone (GC)-induced apoptosis, while the most GC-sensitive DP thymocytes died through the activation of...
4.
Kovacs M, Tenyi T, Kugyelka R, Prenek L, Hau L, Magyar E, et al.
Front Psychiatry . 2020 Feb; 10:996. PMID: 32038330
Inflammation and immune dysregulation could contribute to the pathogenesis of schizophrenia. Osteopontin (OPN) is a cytokine-like glycoprotein involved in inflammation and in modulating immune responses, and it can also directly...
5.
Kugyelka R, Prenek L, Olasz K, Kohl Z, Botz B, Glant T, et al.
Cells . 2019 May; 8(5). PMID: 31137740
T cells play an essential role in the pathogenesis of both human rheumatoid arthritis (RA) and its murine models. A key molecule in T cell activation is ZAP-70, therefore we...
6.
Prenek L, Boldizsar F, Kugyelka R, Ugor E, Berta G, Nemeth P, et al.
Apoptosis . 2016 Nov; 22(2):239-253. PMID: 27888447
Glucocorticoids (GC) are important in the regulation of selection and apoptosis of CD4CD8 double-positive (DP) thymocytes. The pronounced GC-sensitivity of DP thymocytes, observed earlier, might be due to the combination...
7.
Kugyelka R, Kohl Z, Olasz K, Mikecz K, Rauch T, Glant T, et al.
Mediators Inflamm . 2016 Feb; 2016:6145810. PMID: 26903711
Rheumatoid arthritis (RA) is one of the most common autoimmune disorders characterized by the chronic and progressive inflammation of various organs, most notably the synovia of joints leading to joint...