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Reji Babygirija

Explore the profile of Reji Babygirija including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 447
Followers 0
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Recent Articles
1.
Calubag M, Ademi I, Grunow I, Breuer L, Babygirija R, Lialios P, et al.
bioRxiv . 2025 Jan; PMID: 39868338
Dietary protein is a key regulator of healthy aging in both mice and humans. In mice, reducing dietary levels of the branched-chain amino acids (BCAAs) recapitulates many of the benefits...
2.
Yeh C, Chini L, Davidson J, Garcia G, Gallagher M, Freichels I, et al.
Nat Aging . 2024 Nov; 4(12):1760-1771. PMID: 39604703
Restricting the intake of protein or the branched-chain amino acid isoleucine promotes healthspan and extends lifespan in young or adult mice. However, their effects when initiated in aged animals are...
3.
Babygirija R, Han J, Sonsalla M, Matoska R, Calubag M, Green C, et al.
bioRxiv . 2024 Oct; PMID: 39386545
Caloric restriction (CR) is a widely recognized geroprotective intervention that slows or prevents Alzheimer's disease (AD) in animal models. CR is typically implemented via feeding mice a single meal per...
4.
Sonsalla M, Babygirija R, Johnson M, Cai S, Cole M, Yeh C, et al.
Geroscience . 2024 Sep; PMID: 39271570
Age is the greatest risk factor for Alzheimer's disease (AD) as well as for other disorders that increase the risk of AD such as diabetes and obesity. There is growing...
5.
Pak H, Grossberg A, Sanderfoot R, Babygirija R, Green C, Koller M, et al.
Cell Rep . 2024 Aug; 43(9):114663. PMID: 39167490
Calorie restriction (CR) extends lifespan and healthspan in diverse species. Comparing ad libitum- and CR-fed mice is challenging due to their significantly different feeding patterns, with CR-fed mice consuming their...
6.
Sonsalla M, Babygirija R, Johnson M, Cai S, Cole M, Yeh C, et al.
bioRxiv . 2024 Jul; PMID: 39005334
Age is the greatest risk factor for Alzheimer's disease (AD) as well as for other disorders that increase the risk of AD such as diabetes and obesity. There is growing...
7.
Trautman M, Green C, MacArthur M, Chaiyakul K, Alam Y, Yeh C, et al.
bioRxiv . 2024 Jun; PMID: 38895446
The amino acid composition of the diet has recently emerged as a critical regulator of metabolic health. Consumption of the branched-chain amino acid isoleucine is positively correlated with body mass...
8.
Babygirija R, Sonsalla M, Mill J, James I, Han J, Green C, et al.
Nat Commun . 2024 Jun; 15(1):5217. PMID: 38890307
Dietary protein is a critical regulator of metabolic health and aging. Low protein diets are associated with healthy aging in humans, and dietary protein restriction extends the lifespan and healthspan...
9.
Haws S, Liu Y, Green C, Babygirija R, Armstrong E, Mehendale A, et al.
bioRxiv . 2023 Dec; PMID: 38106163
Dietary protein and essential amino acid (EAA) restriction promotes favorable metabolic reprogramming, ultimately resulting in improvements to both health and lifespan. However, as individual EAAs have distinct catabolites and engage...
10.
Green C, Trautman M, Chaiyakul K, Jain R, Alam Y, Babygirija R, et al.
Cell Metab . 2023 Nov; 35(11):1976-1995.e6. PMID: 37939658
Low-protein diets promote health and longevity in diverse species. Restriction of the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine recapitulates many of these benefits in young C57BL/6J mice. Restriction...