Regino P Gonzalez-Peralta
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Explore the profile of Regino P Gonzalez-Peralta including associated specialties, affiliations and a list of published articles.
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53
Citations
702
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Recent Articles
1.
Miethke A, Moukarzel A, Porta G, Covarrubias Esquer J, Czubkowski P, Ordonez F, et al.
Lancet Gastroenterol Hepatol
. 2024 May;
9(7):620-631.
PMID: 38723644
Background: Progressive familial intrahepatic cholestasis (PFIC) is a group of autosomal recessive disorders, the most prevalent being BSEP deficiency, resulting in disrupted bile formation, cholestasis, and pruritus. Building on a...
2.
Jonas M, Romero R, Rosenthal P, Lin C, Verucchi G, Wen J, et al.
J Pediatr Gastroenterol Nutr
. 2024 Apr;
78(6):1342-1354.
PMID: 38644678
Background: The safety and efficacy of sofosbuvir-velpatasvir in children aged 3-17 years with chronic hepatitis C virus (HCV) infection of any genotype were evaluated. Methods: In this Phase 2, multicenter,...
3.
Raghu V, Zhang X, Squires J, Eisenberg E, Feldman A, Halma J, et al.
J Pediatr Gastroenterol Nutr
. 2024 Feb;
78(2):328-338.
PMID: 38374561
Objectives: The Starzl Network for Excellence in Pediatric Transplantation identified optimizing immunosuppression (IS) as a priority practice improvement area for patients, families, and providers. We aimed to evaluate associations between...
4.
Indolfi G, Gonzalez-Peralta R, Jonas M, Sayed M, Fischler B, Sokal E, et al.
J Pediatr Gastroenterol Nutr
. 2024 Feb;
78(4):957-972.
PMID: 38369891
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide, with more than three million viraemic adolescents and children. Treatment of adults with HCV infection and...
5.
Real-world experience of maralixibat in Alagille syndrome: Novel findings outside of clinical trials
Himes R, Rosenthal P, Dilwali N, Smith K, Venick R, Gonzalez-Peralta R
J Pediatr Gastroenterol Nutr
. 2024 Feb;
78(3):506-513.
PMID: 38334237
Objective: Maralixibat, an ileal bile acid transporter inhibitor, is the first drug approved by the U.S. Food and Drug Administration for the treatment of cholestatic pruritus in patients aged ≥3...
6.
Alkhouri N, Gonzalez-Peralta R, Medici V
Hepatol Commun
. 2023 May;
7(6).
PMID: 37184530
Wilson disease (WD) is caused by autosomal variants affecting the ATP7B gene on chromosome 13, resulting in alterations in physiological copper homeostasis and copper accumulation. Excess copper clinically manifests in...
7.
Gonzalez-Peralta R, Wirth S, Squires R, Mutschler F, Lang T, Pawlowska M, et al.
Hepatol Commun
. 2023 Feb;
7(3):e0031.
PMID: 36790337
Background: Approximately 3.5 million children and adolescents worldwide are chronically infected with HCV. This study uses pharmacokinetic modeling to identify pediatric doses of elbasvir/grazoprevir (EBR/GZR) that achieve plasma concentrations similar...
8.
Ng V, Dunphy C, Shemesh E, Lobritto S, Eisenberg E, Pomponi C, et al.
Pediatr Transplant
. 2022 Oct;
27(1):e14409.
PMID: 36272132
Background: Patient-reported outcome measures (PROMs) are not routinely used in clinical care by pediatric liver transplant (LT) teams. The Starzl Network for Excellence in Pediatric Transplantation (SNEPT) assessed feasibility of...
9.
Valentino P, Wang T, Shabanova V, Ng V, Bucuvalas J, Feldman A, et al.
Liver Transpl
. 2021 Nov;
28(5):819-833.
PMID: 34837468
Biliary strictures affect 4%-12% of pediatric liver transplantations. Biliary strictures can contribute to graft loss if left untreated; however, there remains no consensus on the best course of treatment. Study...
10.
Camarata M, Ala A, Coskun A, Deng Y, Gonzalez-Peralta R, Maciejewski K, et al.
J Acad Consult Liaison Psychiatry
. 2021 May;
62(5):528-537.
PMID: 34044196
Background: Wilson disease (WD) is a chronic disorder of copper metabolism which may affect patient's quality of life (QOL). Objective: Our aim was to assess the relationship between mental QOL...