Reed E S Harrison
Overview
Explore the profile of Reed E S Harrison including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
83
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0
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Recent Articles
1.
Zhu L, Man C, Harrison R, Wu Z, Limsakul P, Peng Q, et al.
ACS Nano
. 2024 Mar;
18(11):8531-8545.
PMID: 38456901
Programmed death-ligand 1 (PD-L1) is a promising target for cancer immunotherapy due to its ability to inhibit T cell activation; however, its expression on various noncancer cells may cause on-target...
2.
Peng Q, Huang Z, Sun K, Liu Y, Yoon C, Harrison R, et al.
Nat Commun
. 2022 Dec;
13(1):7933.
PMID: 36566209
Genome architecture and organization play critical roles in cell life. However, it remains largely unknown how genomic loci are dynamically coordinated to regulate gene expression and determine cell fate at...
3.
Liu L, Limsakul P, Meng X, Huang Y, Harrison R, Huang T, et al.
Nat Commun
. 2021 Aug;
12(1):5031.
PMID: 34413312
The limited sensitivity of Förster Resonance Energy Transfer (FRET) biosensors hinders their broader applications. Here, we develop an approach integrating high-throughput FRET sorting and next-generation sequencing (FRET-Seq) to identify sensitive...
4.
Narkhede Y, Gautam A, Hsu R, Rodriguez W, Zewde N, Harrison R, et al.
Front Mol Biosci
. 2021 Apr;
8:618068.
PMID: 33829039
Poxviruses are dangerous pathogens, which can cause fatal infection in unvaccinated individuals. The causative agent of smallpox in humans, , is closely related to the bovine , yet the molecular...
5.
McGovern K, Nance J, David C, Harrison R, Noor S, Worth D, et al.
Sci Rep
. 2021 Feb;
11(1):4549.
PMID: 33633185
Central nervous system (CNS) injury and infection can result in profound tissue remodeling in the brain, the mechanism and purpose of which is poorly understood. Infection with the protozoan parasite...
6.
Harrison R, Weng K, Wang Y, Peng Q
Curr Opin Solid State Mater Sci
. 2021 Feb;
25(1).
PMID: 33519290
Liquid-liquid phase separation is increasingly recognized as a phenomenon that affects cell behavior. For example, phase separation of transcription factors and coactivators has been shown to drive efficient transcription. For...
7.
Harrison R, Zewde N, Narkhede Y, Hsu R, Morikis D, Vullev V, et al.
ACS Med Chem Lett
. 2020 May;
11(5):1054-1059.
PMID: 32435425
C3d is a hallmark protein of the complement system, whose presence is critical to measure the progression of several immune diseases. Here, we propose to directly target C3d through small...
8.
Rosenberg Jr E, Harrison R, Tsou L, Drucker N, Humphries B, Rajasekaran D, et al.
Cell Chem Biol
. 2019 Mar;
26(5):662-673.e7.
PMID: 30827936
The G protein-coupled receptor (GPCR) CXCR4 is a co-receptor for HIV and is involved in cancers and autoimmune diseases. We characterized five purine or quinazoline core polyamine pharmacophores used for...
9.
Harrison R, Morikis D
Biophys J
. 2019 Jan;
116(2):215-226.
PMID: 30616835
A single nucleotide polymorphism, tyrosine at position 402 to histidine (Y402H), within the gene encoding complement factor H (FH) predisposes individuals to acquiring age-related macular degeneration (AMD) after aging. This...
10.
Mohan R, Wilson M, Gorham Jr R, Harrison R, Morikis V, Kieslich C, et al.
ACS Omega
. 2018 Sep;
3(6):6427-6438.
PMID: 30221234
The complement system is our first line of defense against foreign pathogens, but when it is not properly regulated, complement is implicated in the pathology of several autoimmune and inflammatory...