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Rebecca Schuler

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Articles 12
Citations 560
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Recent Articles
1.
Molitor M, Rudi W, Garlapati V, Finger S, Schuler R, Kossmann S, et al.
Cardiovasc Res . 2020 Feb; 117(1):162-177. PMID: 32077922
Aims: Heart failure (HF) ensuing myocardial infarction (MI) is characterized by the initiation of a systemic inflammatory response. We aimed to elucidate the impact of myelomonocytic cells and their activation...
2.
Mufazalov I, Andruszewski D, Schelmbauer C, Heink S, Blanfeld M, Masri J, et al.
J Immunol . 2020 Jan; 204(4):747-751. PMID: 31924653
IL-6 binds to the IL-6R α-chain (IL-6Rα) and signals via the signal transducer gp130. Recently, IL-6 was found to also bind to the cell surface glycoprotein CD5, which would then...
3.
Schutz E, Gogiraju R, Pavlaki M, Drosos I, Georgiadis G, Argyriou C, et al.
Int J Mol Sci . 2020 Jan; 21(1). PMID: 31906225
Cardiovascular risk factors may act by modulating the composition and function of the adventitia. Here we examine how age affects perivascular adipose tissue (PVAT) and its paracrine activities during neointima...
4.
Wild J, Schuler R, Knopp T, Molitor M, Kossmann S, Munzel T, et al.
Int J Mol Sci . 2019 Sep; 20(17). PMID: 31480330
Background: Psoriasis is hallmarked by vascular dysfunction, arterial hypertension, and an increased risk for cardiovascular diseases. We have shown recently that skin-driven interleukin (IL)-17A expression promotes psoriasis-like disease in mice,...
5.
Schuler R, Efentakis P, Wild J, Lagrange J, Garlapati V, Molitor M, et al.
Oxid Med Cell Longev . 2019 Aug; 2019:6721531. PMID: 31396305
Aims: The neutrophil recruiting cytokine Interleukin-17A (IL-17A) is a key component in vascular dysfunction and arterial hypertension. Moreover, IL-17A has a central role for the vascular infiltration of myeloid cells...
6.
Finger S, Knorr M, Molitor M, Schuler R, Garlapati V, Waisman A, et al.
Cardiovasc Res . 2019 Apr; 115(13):1907-1917. PMID: 30949687
Aims: Myelomonocytic cells are critical in injury and healing post-myocardial infarction (MI). Mechanisms of regulation, however, are incompletely understood. The aim of the study was to elucidate the role of...
7.
Schuler R, Brand A, Klebow S, Wild J, Veras F, Ullmann E, et al.
J Invest Dermatol . 2018 Oct; 139(3):638-647. PMID: 30367871
Besides skin inflammation, patients with severe psoriasis suffer from an increased risk of cardiovascular mortality. IL-17A plays a central role in the development of psoriasis and might connect skin and...
8.
Karbach S, Schonfelder T, Brandao I, Wilms E, Hormann N, Jackel S, et al.
J Am Heart Assoc . 2016 Sep; 5(9). PMID: 27577581
Background: The gut microbiome is essential for physiological host responses and development of immune functions. The impact of gut microbiota on blood pressure and systemic vascular function, processes that are...
9.
Karbach S, Croxford A, Oelze M, Schuler R, Minwegen D, Wegner J, et al.
Arterioscler Thromb Vasc Biol . 2014 Oct; 34(12):2658-68. PMID: 25341795
Objective: Interleukin (IL)-17A is regarded as an important cytokine to drive psoriasis, an inflammatory skin disease marked by increased cardiovascular mortality. We aimed to test the hypothesis that overproduction of...
10.
Croxford A, Karbach S, Kurschus F, Wortge S, Nikolaev A, Yogev N, et al.
J Invest Dermatol . 2013 Sep; 134(3):728-735. PMID: 24067382
The lack of a generally accepted animal model for human psoriasis has hindered progress with respect to understanding the pathogenesis of the disease. Here we present a model in which...