Rebecca Parodi-Rullan
Overview
Explore the profile of Rebecca Parodi-Rullan including associated specialties, affiliations and a list of published articles.
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10
Citations
270
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Recent Articles
1.
Carey A, Parodi-Rullan R, Vazquez-Torres R, Canepa E, Fossati S
Aging Cell
. 2024 Feb;
23(5):e14106.
PMID: 38358083
Cerebrovascular dysfunction has been implicated as a major contributor to Alzheimer's Disease (AD) pathology, with cerebral endothelial cell (cEC) stress promoting ischemia, cerebral-blood flow impairments and blood-brain barrier (BBB) permeability....
2.
Elia A, Parodi-Rullan R, Vazquez-Torres R, Carey A, Javadov S, Fossati S
bioRxiv
. 2023 Jul;
PMID: 37502936
Aims: Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by cerebral amyloid β (Aβ) deposition and tau pathology. The AD-mediated degeneration of the brain neuro-signaling pathways, together with a...
3.
Canepa E, Parodi-Rullan R, Vazquez-Torres R, Gamallo-Lana B, Guzman-Hernandez R, Lemon N, et al.
Alzheimers Dement
. 2023 May;
19(11):5048-5073.
PMID: 37186121
Introduction: Cerebrovascular pathology is an early and causal hallmark of Alzheimer's disease (AD), in need of effective therapies. Methods: Based on the success of our previous in vitro studies, we...
4.
Parodi-Rullan R, Ghiso J, Cabrera E, Rostagno A, Fossati S
Aging Cell
. 2020 Nov;
19(11):e13258.
PMID: 33155752
Impaired clearance in the Alzheimer's Disease (AD) brain is key in the formation of Aβ parenchymal plaques and cerebrovascular deposits known as cerebral amyloid angiopathy (CAA), present in >80% of...
5.
Parodi-Rullan R, Sone J, Fossati S
J Alzheimers Dis
. 2019 Jul;
72(4):1019-1039.
PMID: 31306129
Alzheimer's disease (AD) is the most prevalent form of dementia. Cerebrovascular dysfunction is one of the earliest events in the pathogenesis of AD, as well as in vascular and mixed...
6.
Javadov S, Jang S, Parodi-Rullan R, Khuchua Z, Kuznetsov A
Cell Mol Life Sci
. 2017 Apr;
74(15):2795-2813.
PMID: 28378042
Growing number of studies provide strong evidence that the mitochondrial permeability transition pore (PTP), a non-selective channel in the inner mitochondrial membrane, is involved in the pathogenesis of cardiac ischemia-reperfusion...
7.
Escobales N, Nunez R, Jang S, Parodi-Rullan R, Ayala-Pena S, Sacher J, et al.
J Mol Cell Cardiol
. 2014 Dec;
77:136-46.
PMID: 25451170
Mitochondria-generated reactive oxygen species (ROS) play a crucial role in the pathogenesis of aging and age-associated diseases. In this study, we evaluated the effects of XJB-5-131 (XJB), a mitochondria-targeted ROS...
8.
Barreto-Torres G, Parodi-Rullan R, Javadov S
Int J Mol Sci
. 2012 Jul;
13(6):7694-7709.
PMID: 22837722
Metformin, an anti-diabetic drug, exerts cardioprotection against ischemia-reperfusion (IR) through the activation of AMPK. However, the molecular mechanisms underlying these beneficial effects remain elusive. In this study, we examined the...
9.
Parodi-Rullan R, Barreto-Torres G, Ruiz L, Casasnovas J, Javadov S
Cell Physiol Biochem
. 2012 May;
29(5-6):841-50.
PMID: 22613984
Background: In addition to hypertension control, direct renin inhibition has been shown to exert direct beneficial effects on the heart in post-infarction cardiac remodeling. This study elucidates the possible contribution...
10.
Javadov S, Hunter J, Barreto-Torres G, Parodi-Rullan R
Cell Physiol Biochem
. 2011 Apr;
27(3-4):179-90.
PMID: 21471706
Cardiovascular diseases and cancer continue to be major causes of death worldwide, and despite intensive research only modest progress has been reached in reducing the morbidity and mortality of these...