Rebecca L Murdaugh
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Explore the profile of Rebecca L Murdaugh including associated specialties, affiliations and a list of published articles.
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6
Citations
29
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Recent Articles
1.
Zhang L, Hsu J, Braekeleer E, Chen C, Patel T, Martell A, et al.
Elife
. 2024 Jun;
12.
PMID: 38896450
The DNA damage response is critical for maintaining genome integrity and is commonly disrupted in the development of cancer. PPM1D (protein phosphatase Mg/Mn-dependent 1D) is a master negative regulator of...
2.
Tseng Y, Kageyama Y, Murdaugh R, Kitano A, Kim J, Hoegenauer K, et al.
Nat Commun
. 2024 Jan;
15(1):538.
PMID: 38225226
Hematopoietic stem cells (HSCs) are capable of regenerating the blood system, but the instructive cues that direct HSCs to regenerate particular lineages lost to the injury remain elusive. Here, we...
3.
Murdaugh R, Anastas J
Front Pharmacol
. 2023 May;
14:1002296.
PMID: 37205910
Despite improvements in cancer patient outcomes seen in the past decade, tumor resistance to therapy remains a major impediment to achieving durable clinical responses. Intratumoral heterogeneity related to genetic, epigenetic,...
4.
Wang Y, Huo T, Tseng Y, Dang L, Yu Z, Yu W, et al.
Commun Biol
. 2022 Jan;
5(1):72.
PMID: 35058565
Early diagnosis of acute myeloid leukemia (AML) in the pre-leukemic stage remains a clinical challenge, as pre-leukemic patients show no symptoms, lacking any known morphological or numerical abnormalities in blood...
5.
Shi X, Jiang Y, Kitano A, Hu T, Murdaugh R, Li Y, et al.
Sci Adv
. 2021 Jul;
7(30).
PMID: 34290089
Metabolic dysregulation underlies malignant phenotypes attributed to cancer stem cells, such as unlimited proliferation and differentiation blockade. Here, we demonstrate that NAD metabolism enables acute myeloid leukemia (AML) to evade...
6.
Murdaugh R, Hoegenauer K, Kitano A, Holt M, Hill M, Shi X, et al.
Stem Cell Reports
. 2021 Jul;
16(8):2014-2028.
PMID: 34242617
Histone variants contribute to the complexity of the chromatin landscape and play an integral role in defining DNA domains and regulating gene expression. The histone H3 variant H3.3 is incorporated...