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Rebecca K Studer

Explore the profile of Rebecca K Studer including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 428
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Recent Articles
1.
Studer R, Vo N, Sowa G, Ondeck C, Kang J
Spine (Phila Pa 1976) . 2010 Dec; 36(8):593-9. PMID: 21178846
STUDY DESIGN.: Human nucleus pulposus cells were activated with IL-6 plus IL-6 soluble receptor (sR) in the presence or absence of IL-1β or TNF-α. Cell production of factors modulating the...
2.
Sowa G, Coelho J, Bell K, Zorn A, Vo N, Smolinski P, et al.
Spine J . 2010 Nov; 11(1):36-43. PMID: 21056011
Background Context: It is clear that mechanical forces are involved in initiating disc degeneration but also have the potential to exert beneficial effects. However, the signaling pathways initiated by mechanical...
3.
Vo N, Sowa G, Kang J, Seidel C, Studer R
J Orthop Res . 2010 Sep; 28(10):1259-66. PMID: 20839316
Prostaglandin (PG) actions on disc metabolism are unclear even though certain PGs are highly expressed by disc cells under inflammatory conditions and nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used to...
4.
Kim J, Deasy B, Seo H, Studer R, Vo N, Georgescu H, et al.
Spine (Phila Pa 1976) . 2009 Oct; 34(23):2486-93. PMID: 19841610
Study Design: We demonstrated the differentiation of notochordal cells by direct observation using a live automated cell imaging system. We also hypothesized that notochordal cells have characteristics of chondrocyte-like cells....
5.
Kim J, Studer R, Sowa G, Vo N, Kang J
Spine (Phila Pa 1976) . 2008 Sep; 33(21):2253-9. PMID: 18784630
Study Design: Anulus fibrosus (AF) cells obtained from patients undergoing surgery were cocultured with macrophage-like cells and production of inflammatory mediators was analyzed by quantitative assay. Objective: To investigate the...
6.
Hubert M, Vadala G, Sowa G, Studer R, Kang J
J Am Acad Orthop Surg . 2008 Jun; 16(6):312-9. PMID: 18524982
Recent biologic and biochemical advances have furthered our understanding of the complex environment of the intervertebral disk. This new understanding has allowed researchers to pursue novel treatments of intervertebral disk...
7.
Gilbertson L, Ahn S, Teng P, Studer R, Niyibizi C, Kang J
Spine J . 2008 May; 8(3):449-56. PMID: 18455111
Background Context: Bone morphogenetic proteins (BMPs) are potential therapeutic factors for degenerative discs, and BMP-12 does not have the osteogenic potential of BMP-2, making it better suited for intradiscal injection....
8.
Vadala G, Studer R, Sowa G, Spiezia F, Iucu C, Denaro V, et al.
Spine (Phila Pa 1976) . 2008 Apr; 33(8):870-6. PMID: 18404106
Study Design: Changes in gene expression profile and cell fusion of mesenchymal stem cells (MSC) and nucleus pulposus cells (NPC) after coculture were analyzed. Objective: To investigate the mechanisms of...
9.
Studer R, Gilbertson L, Georgescu H, Sowa G, Vo N, Kang J
J Orthop Res . 2008 Feb; 26(7):991-8. PMID: 18302237
Analysis of disc gene expression implicated IL-1 in the development of intervertebral disc degeneration (IDD) in a rabbit stab model. The purpose of these studies is to determine the role...
10.
Studer R, Aboka A, Gilbertson L, Georgescu H, Sowa G, Vo N, et al.
Spine (Phila Pa 1976) . 2008 Feb; 32(25):2827-33. PMID: 18246004
Study Design: Human nucleus pulposus cells were cultured in alginate beads and activated with IL-1 beta or TNF-alpha, with and without inhibition of p38 mitogen activated protein kinase (p38 MAPK)...