Raymond S H Yang
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Explore the profile of Raymond S H Yang including associated specialties, affiliations and a list of published articles.
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45
Citations
383
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Recent Articles
31.
Dennison J, Andersen M, Yang R
Inhal Toxicol
. 2005 Jul;
17(11):539-48.
PMID: 16033751
Gas uptake chamber studies have been widely used to study inhalation pharmacokinetics (PKs) in rodents, often for the ultimate purpose of developing physiologically-based pharmacokinetic (PBPK) models that can be used...
32.
Dennison J, Bigelow P, Mumtaz M, Andersen M, Dobrev I, Yang R
J Occup Environ Hyg
. 2005 Mar;
2(3):127-35.
PMID: 15764536
Under OSHA and American Conference of Governmental Industrial Hygienists (ACGIH) guidelines, the mixture formula (unity calculation) provides a method for evaluating exposures to mixtures of chemicals that cause similar toxicities....
33.
Dennison J, Andersen M, Clewell H, Yang R
Environ Sci Technol
. 2004 Dec;
38(21):5674-81.
PMID: 15575287
Physiologically based pharmacokinetic (PBPK) models have often been used to describe the absorption, distribution, metabolism, and excretion of chemicals in animals but have been limited to single chemicals and simple...
34.
Dennison J, Andersen M, Yang R
Inhal Toxicol
. 2003 Aug;
15(10):961-86.
PMID: 12928975
Gasoline consists of a few toxicologically significant components and a large number of other hydrocarbons in a complex mixture. By using an integrated, physiologically based pharmacokinetic (PBPK) modeling and lumping...
35.
Bae D, Handa R, Yang R, Campain J
Toxicol Sci
. 2003 May;
74(1):32-42.
PMID: 12773770
In previous studies, treatment with 1-methyl-3-nitro-1-nitrosoguanidine (MNNG) enhanced malignant transformation of immortal human epidermal (RHEK-1) keratinocytes. In contrast, arsenic (As) alone or in a mixture of As, cadmium (Cd), chromium...
36.
Ou Y, Conolly R, Thomas R, Gustafson D, Long M, Dobrev I, et al.
Toxicol Sci
. 2003 Apr;
73(2):301-14.
PMID: 12700395
A combination of experimental and simulation approaches was used to analyze clonal growth of glutathione-S-transferase pi (GST-P) enzyme-altered foci during liver carcinogenesis in an initiation-promotion regimen for 1,4-dichlorobenzene (DCB), 1,2,4,5-tetrachlorobenzene...
37.
Klein M, Hou G, Quann R, Wei W, Liao K, Yang R, et al.
Environ Health Perspect
. 2003 Mar;
110 Suppl 6:1025-9.
PMID: 12634134
A chemical engineering approach for the rigorous construction, solution, and optimization of detailed kinetic models for biological processes is described. This modeling capability addresses the required technical components of detailed...
38.
Andersen M, Yang R, French C, Chubb L, Dennison J
Environ Health Perspect
. 2003 Mar;
110 Suppl 6:971-8.
PMID: 12634127
Signaling motifs (nuclear transcriptional receptors, kinase/phosphatase cascades, G-coupled protein receptors, etc.) have composite dose-response behaviors in relation to concentrations of protein receptors and endogenous signaling molecules. "Molecular circuits" include the...
39.
Liao K, Dobrev I, Dennison Jr J, Andersen M, Reisfeld B, Reardon K, et al.
Environ Health Perspect
. 2003 Mar;
110 Suppl 6:957-63.
PMID: 12634125
The complexity and the astronomic number of possible chemical mixtures preclude any systematic experimental assessment of toxicology of all potentially troublesome chemical mixtures. Thus, the use of computer modeling and...
40.
Bae D, Hanneman W, Yang R, Campain J
Environ Health Perspect
. 2003 Mar;
110 Suppl 6:931-41.
PMID: 12634122
The identification of molecular markers related to critical biological processes during carcinogenesis may aid in the evaluation of carcinogenic potentials of chemicals and chemical mixtures. Work from our laboratory demonstrated...