Raymond F Suckow
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Explore the profile of Raymond F Suckow including associated specialties, affiliations and a list of published articles.
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38
Citations
711
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Recent Articles
11.
Benham R, Hewage N, Suckow R, Engin E, Rudolph U
Behav Brain Res
. 2017 Jun;
332:172-179.
PMID: 28587819
Deficits in neuronal inhibition via gamma-aminobutyric acid (GABA) type A receptors (GABAA-Rs) are implicated in the pathophysiology of major depressive disorder and the therapeutic effects of current antidepressant treatments, however,...
12.
Lopez L, Shaikh A, Merson J, Greenberg J, Suckow R, Kane J
J Clin Psychopharmacol
. 2017 Mar;
37(3):310-314.
PMID: 28353490
Purpose: The present study aimed to assess the level of agreement between clinicians' routine assessments of medication status and plasma levels of commonly prescribed antipsychotic medications in patients presenting to...
13.
Sershen H, Hashim A, Dunlop D, Suckow R, Cooper T, Javitt D
Neurochem Res
. 2016 Feb;
41(1-2):398-408.
PMID: 26857796
Deficits in N-methyl-D-aspartate receptor (NMDAR) function are increasingly linked to persistent negative symptoms and cognitive deficits in schizophrenia. Accordingly, clinical studies have been targeting the modulatory site of the NMDA...
14.
Iaccarino H, Suckow R, Xie S, Bucci D
Schizophr Res
. 2013 Oct;
150(2-3):392-7.
PMID: 24091034
Kynurenic acid is a tryptophan metabolite that is synthesized and released in the brain by astrocytes and acts as an antagonist of nicotinic acetylcholine receptors and N-methyl-d-aspartate glutamate receptors, both...
15.
Driesen N, McCarthy G, Bhagwagar Z, Bloch M, Calhoun V, DSouza D, et al.
Neuropsychopharmacology
. 2013 Jul;
38(13):2613-22.
PMID: 23856634
Preclinical research suggests that N-methyl-D-aspartate glutamate receptors (NMDA-Rs) have a crucial role in working memory (WM). In this study, we investigated the role of NMDA-Rs in the brain activation and...
16.
DSouza D, Ahn K, Bhakta S, Elander J, Singh N, Nadim H, et al.
Biol Psychiatry
. 2012 Jun;
72(9):785-94.
PMID: 22717030
Background: The uncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist, ketamine, induces a range of symptoms resembling those seen in schizophrenia. Enhancement of nicotinic acetylcholine receptor (nAChR) function may have potential as a...
17.
Akagbosu C, Evans G, Gulick D, Suckow R, Bucci D
Schizophr Bull
. 2010 Dec;
38(4):769-78.
PMID: 21172906
The glia-derived molecule kynurenic acid (KYNA) is an antagonist of α7 nicotinic acetylcholine receptors and the glycine(B) binding site on n-methyl-d-aspartateglutamate receptors, both of which have critical roles in neural...
18.
Krystal J, Petrakis I, Limoncelli D, Nappi S, Trevisan L, Pittman B, et al.
Neuropsychopharmacology
. 2010 Dec;
36(3):701-10.
PMID: 21124304
Reduced responses to N-methyl-D-aspartate (NMDA) glutamate receptor antagonists in alcohol-dependent animals and humans provided evidence that chronic alcohol consumption increased NMDA receptor function. To further probe alterations in NMDA glutamate...
19.
Lin Y, Suckow R, Sarfraz Y, Stone E
Int J Neuropsychopharmacol
. 2010 Sep;
14(5):691-6.
PMID: 20875221
This study was designed to replicate an earlier finding of a rapid acute therapeutic action of intracerebrally administered antidepressant in chronically depressed rodents. The effects of acute fourth ventricular (ivt.)...
20.
Slifstein M, Suckow R, Javitch J, Cooper T, Lieberman J, Abi-Dargham A
J Cereb Blood Flow Metab
. 2010 Jun;
31(1):293-304.
PMID: 20571519
DAR-0100A, the active enantiomer of dihydrexidine, is a potent dopamine D1 agonist under investigation for treatment of cognitive impairment and negative symptoms of schizophrenia. We measured the dose-occupancy relationship for...