Raymond C Koehler
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Explore the profile of Raymond C Koehler including associated specialties, affiliations and a list of published articles.
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161
Citations
4169
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Recent Articles
11.
Wang J, Shi Y, Cao S, Liu X, Martin L, Simoni J, et al.
Front Med Technol
. 2023 Mar;
5:1074643.
PMID: 36896342
Polynitroxylated PEGylated hemoglobin (PNPH, aka SanFlow) possesses superoxide dismutase/catalase mimetic activities that may directly protect the brain from oxidative stress. Stabilization of PNPH with bound carbon monoxide prevents methemoglobin formation...
12.
Toung T, Mehr N, Mirski M, Koehler R
Physiol Rep
. 2023 Feb;
11(4):e15613.
PMID: 36802121
In most preclinical models of focal ischemic stroke, vascular occlusion is performed under general anesthesia. However, anesthetic agents exert confounding effects on mean arterial blood pressure (MABP), cerebrovascular tone, oxygen...
13.
El-Demerdash N, Pan T, Choi O, Saraswati M, Koehler R, Robertson C, et al.
J Neurotrauma
. 2022 Nov;
40(11-12):1197-1215.
PMID: 36416234
Therapies are limited for pediatric traumatic brain injury (TBI), especially for the very young who can experience long-term consequences to learning, memory, and social behavior. Animal models of pediatric TBI...
14.
Dong Y, Gu Y, Lu J, Wan J, Jiang S, Koehler R, et al.
Neurotrauma Rep
. 2022 Aug;
3(1):261-275.
PMID: 35982981
After traumatic brain injury (TBI), early assessment of secondary injury severity is critically important for estimating prognosis and treatment stratification. Currently, secondary injury severity is difficult to estimate. The objective...
15.
Gu Y, Dong Y, Wan J, Ren H, Koehler R, Wang J
Exp Neurol
. 2022 Jun;
355:114125.
PMID: 35644427
The goal of this study was to determine whether deficiency of anti-inflammatory cytokine interleukin-10 (IL-10) affects traumatic brain injury (TBI) outcomes in a sex-dependent manner. Moderate TBI was induced by...
16.
Liu X, Donnelly J, Brady K, Akiyoshi K, Bush B, Koehler R, et al.
Br J Anaesth
. 2022 May;
129(1):22-32.
PMID: 35597624
Background: Cardiac surgery studies have established the clinical relevance of personalised arterial blood pressure management based on cerebral autoregulation. However, variabilities exist in autoregulation evaluation. We compared the association of...
17.
Wang B, Kulikowicz E, Koehler R, Yang Z
Neonatology
. 2022 Apr;
119(3):354-360.
PMID: 35477141
Introduction: Striatal neurons of term newborns are highly vulnerable to hypoxia-ischemia (H-I). In a piglet model of H-I, a dopamine D1 receptor antagonist and an adenosine A2A receptor antagonist alone...
18.
Lyden P, Bosetti F, Diniz M, Rogatko A, Koenig J, Lamb J, et al.
Stroke
. 2022 Mar;
53(5):1802-1812.
PMID: 35354299
Cerebral ischemia and reperfusion initiate cellular events in brain that lead to neurological disability. Investigating these cellular events provides ample targets for developing new treatments. Despite considerable work, no such...
19.
Kang J, Liu X, Cao S, Zeiler S, Graham E, Boctor E, et al.
J Neural Eng
. 2021 Dec;
18(6).
PMID: 34937013
Objective: Perinatal ischemic stroke is estimated to occur in 1/2300-1/5000 live births, but early differential diagnosis from global hypoxia-ischemia is often difficult. In this study, we tested the ability of...
20.
Tu R, Armstrong J, Lee K, Hammock B, Sapirstein A, Koehler R
Sci Rep
. 2021 Dec;
11(1):24259.
PMID: 34907191
No abstract available.