Ravikumar Aalinkeel
Overview
Explore the profile of Ravikumar Aalinkeel including associated specialties, affiliations and a list of published articles.
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66
Citations
1331
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Recent Articles
1.
Mahajan S, Aalinkeel R, Reynolds J, Machhar J, Ghebrehiwet B, Schwartz S
J Allergy Clin Immunol Glob
. 2024 Nov;
4(1):100353.
PMID: 39583036
Background: Hereditary angioedema (HAE) is a rare inherited disorder that predisposes an individual to develop vasogenic edema. Bradykinin release, which increases vascular permeability, results in angioedema. C1 esterase inhibitor (C1-INH)...
2.
Sharma S, Mohler J, Mahajan S, Schwartz S, Bruggemann L, Aalinkeel R
Microorganisms
. 2024 Oct;
12(10).
PMID: 39458421
In the original publication [...].
3.
Singh H, Shyamveer , Jori C, Mahajan S, Aalinkeel R, Kaliyappan K, et al.
Heliyon
. 2024 May;
10(9):e30519.
PMID: 38742060
Apolipoproteins and Scavenger Receptor Class B1 (SCARB1) proteins are involved in the etiology of HIV-associated lipodystrophy (HIVLD). 3238C/G 12669G/A and 1050C/T polymorphisms were linked with increased level of APOB, TG,...
4.
Singh H, Shyamveer , Mahajan S, Aalinkeel R, Kaliyappan K, Schwartz S, et al.
Clin Chim Acta
. 2024 Feb;
556:117830.
PMID: 38354999
Protease inhibitors (PIs) are associated with an incidence of lipodystrophy among people living with HIV(PLHIV). Lipodystrophiesare characterised by the loss of adipose tissue. Evidence suggests that a patient's lipodystrophy phenotype...
5.
Sharma S, Mohler J, Mahajan S, Schwartz S, Bruggemann L, Aalinkeel R
Microorganisms
. 2023 Jun;
11(6).
PMID: 37375116
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections...
6.
Singh H, Jori C, Shyamveer , Mahajan S, Aalinkeel R, Kaliyappan K, et al.
Front Cardiovasc Med
. 2023 Jun;
10:1177054.
PMID: 37324630
HIV-associated lipodystrophy (HIVLD) is a metabolic condition with an irregularity in the production of lipoprotein particles, and its occurrence varies among HIV-infected patients. and genes have a role in the...
7.
Sharma S, Mahajan S, Chevli K, Schwartz S, Aalinkeel R
Crit Rev Ther Drug Carrier Syst
. 2023 Apr;
40(4):69-100.
PMID: 37075068
Treatments for late-stage prostate cancer (CaP) have not been very successful. Frequently, advanced CaP progresses to castration-resistant prostate cancer (CRPC), with 50#37;-70% of patients developing bone metastases. CaP with bone...
8.
Sharma S, Cwiklinski K, Mahajan S, Schwartz S, Aalinkeel R
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765857
The standard of care chemotherapy drug presently used to treat castration-resistant prostate cancer (CRPC), docetaxel (Doc), also develops chemoresistance, thereby reducing its clinical utility. Since resistance to chemotherapy drugs can...
9.
Bruggemann L, Falls Z, Mangione W, Schwartz S, Battaglia S, Aalinkeel R, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674513
Pharmacogenomics is a rapidly growing field with the goal of providing personalized care to every patient. Previously, we developed the Computational Analysis of Novel Drug Opportunities (CANDO) platform for multiscale...
10.
Chean K, Aalinkeel R, Abbasi S, Sharikova A, Schwartz S, Khmaladze A, et al.
Biochem Biophys Res Commun
. 2022 Jul;
621:116-121.
PMID: 35820281
METH and HIV Tat treatment results in increased oxidative stress which affects cellular metabolism and causes DNA damage in the treated microglia. Both, METH ± HIV Tat impair mitochondrial respiration,...